Protein Alignment vnd and Nkx2-4

DIOPT Version :10

• Sequence 1: NP_476786.2
• Gene: vnd / 31003
• FlyBaseID: FBgn0261930
• Length: 723
• Species: Drosophila melanogaster
• Sequence 2: XP_038962557.1
• Gene: Nkx2-4 / 366213
• RGDID: 1304985
• Length: 353
• Species: Rattus norvegicus
• Alignment Length: 417
• Identity: 131/417 - (31%)
• Similarity: 166/417 - (39%)
• Gaps: 154/417 - (36%)

  Fly   248 HTSPSALSPTPAGVSADEHHNGS-------GTGGGAGEADHHSTTEHHAPPSHPQQQHPHHQQHH 305
            ||:|.::|...:.:.......|.       |.|...|.|      .:.|||:.|..|
  Rat     7 HTTPFSVSDILSPIEETYKKFGGVMDGAPPGLGAPLGAA------AYRAPPTGPSSQ-------- 57

  Fly   306 HPHLLLPQQHHQQAVAPLPLAHHQSGEAQSHAHANAAAAHLLASHNAAAAAAVAAGQYLPNLPKN 370
                       ..|||.:...|..:|    |..|.||||       ||||||.||..::|
  Rat    58 -----------AAAVAGMQPPHAMAG----HNAAAAAAA-------AAAAAAAAATYHMP----- 95

  Fly   371 FPGSFGDEMSSYHHMAQTMLQHSGRSAWIKENELYGTQQPASPDSTSPVTSEVSYTYIGSNCQTS 435
             ||     :|.:.|.|                                         :||.|...
  Rat    96 -PG-----VSQFPHSA-----------------------------------------MGSYCNGG 113

  Fly   436 PALSGDYKSYSRSADSDALSVGDALHTLHGSSGNGSAGGAPTAHALHNNNNNTTNNNNHSLKAEG 500
            ....|:..:|:           |.:        .|.|..|.|.....|.:...::.:.....:.|
  Rat   114 LGNMGELPAYT-----------DGM--------RGGAAAAATGWYGANTDPRYSSISRFMGPSAG 159

  Fly   501 INGAGSGHDDSLNEDGIEEDIDDVDDADGSGGGDANGSDGL-----PNKKRKRRVLFTKAQTYEL 560
            :|.||.|   ||.                   |.|:.:..|     ...:|||||||::||.|||
  Rat   160 VNVAGMG---SLT-------------------GIADAAKSLAPLHAAAPRRKRRVLFSQAQVYEL 202

  Fly   561 ERRFRQQRYLSAPEREHLASLIRLTPTQVKIWFQNHRYKTKRAQNEKG-----YEGHPGLLHGHA 620
            ||||:||:||||||||||||:|.||||||||||||||||.||...:|.     .||..|
  Rat   203 ERRFKQQKYLSAPEREHLASMIHLTPTQVKIWFQNHRYKMKRQAKDKAAQQLQQEGGLG------ 261

  Fly   621 THPHHPSALPSPRRVAVPVLVRNGKPC 647
              |..|...||||||||||||::||||
  Rat   262 --PPPPPPPPSPRRVAVPVLVKDGKPC 286

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
vnd	NP_476786.2	Homeodomain	546..602	CDD:459649	47/55 (85%)
Nkx2-4	XP_038962557.1	Homeodomain	188..244	CDD:459649	47/55 (85%)