Protein Alignment vnd and inv

DIOPT Version :10

• Sequence 1: NP_476786.2
• Gene: vnd / 31003
• FlyBaseID: FBgn0261930
• Length: 723
• Species: Drosophila melanogaster
• Sequence 2: NP_523699.3
• Gene: inv / 36239
• FlyBaseID: FBgn0001269
• Length: 576
• Species: Drosophila melanogaster
• Alignment Length: 708
• Identity: 150/708 - (21%)
• Similarity: 229/708 - (32%)
• Gaps: 241/708 - (34%)

  Fly     1 MTTSASLERTPSK---------RDRDRERDNSSGLGSAGSLPASPQSAITVSPSSPATPKRPLRT 56
            |:|.||....|.|         .|..:||....|....|.:.........|.|.
  Fly     1 MSTLASTRPPPLKLTIPSLEEAEDHAQERRAGGGGQEVGKMHPDCLPLPLVQPG----------- 54

  Fly    57 STPSLERKREREDREDRE----DRKERQERHERDRDHERFA----AVFS-------TASTTVPTN 106
            ::|.:..:.|.|..|..|    :.:|.:|.|:.|.:.....    :|.|       .|...:...
  Fly    55 NSPQVREEEEDEQTECEEQLNIEDEEVEEEHDLDLEDPASCCSENSVLSVGQEQSEAAQAALSAQ 119

  Fly   107 TSSSSGLAPEQLRIPTGAAAFSGFPGLHSMSSLMLPSSAAVAAAAAAPFLPWSPILLPPWNHALL 171
            ..:...|...|:..|   :|||      |.::.:||.|      ...||.|...:.|||     .
  Fly   120 AQARQRLLISQIYRP---SAFS------STATTVLPPS------EGPPFSPEDLLQLPP-----S 164

  Fly   172 PAAFYPAALRNALPGLFDAKVPSSQRSGFHISDILNLEGSELKNAAAAAAAAAHHGSDLSHHSAS 236
            ...|....||.:  .|:..::...|         ::|..:...||..||||    |..|....|:
  Fly   165 TGTFQEEFLRKS--QLYAEELMKQQ---------MHLMAAARVNALTAAAA----GKQLQMAMAA 214

  Fly   237 ESTSGHRGQGSHTSPSALSPTPAGVSADEHHNGSGTGGGAGEADHHSTTEHHAPPSHPQQQHPHH 301
                           :|::..|:|..|......:..|.|.|.|.|          .|.|......
  Fly   215 ---------------AAVATVPSGQDALAQLTATALGLGPGGAVH----------PHQQLLLQRD 254

  Fly   302 QQHHHPHLLLPQQH-------HQQAV-------------APLP-------------LAHHQSGEA 333
            |.|||.|:   |.|       |::|:             :.||             ::...:|.:
  Fly   255 QVHHHHHM---QNHLNNNENLHERALKFSIDNILKADFGSRLPKIGALSGNIGGGSVSGSSTGSS 316

  Fly   334 QSHAHANAAAAHL-----------LASHNAAAAAAVAAGQYLPNLPKNFPGSFGDEMSSYHHMAQ 387
            ::..:.|...:.|           ||..||||.::::....|.|:..|
  Fly   317 KNSGNTNGNRSPLKAPKKSGKPLNLAQSNAAANSSLSFSSSLANICSN----------------- 364

  Fly   388 TMLQHSGRSAWIKENELYGTQQPASPDSTSPVTSEVSYTYIGSNCQTSPALSGDYKSYSRSADSD 452
                                    |.||.|..||       .|...||.|.....||...:|.:.
  Fly   365 ------------------------SNDSNSTATS-------SSTTNTSGAPVDLVKSPPPAAGAG 398

  Fly   453 ALSVGDALHTLHGSSG-NGSAGGAP---------TAHALHNNNNNTTNNNNHSLKAEGINGAGSG 507
            |.          |:|| :|...|.|         |.::...::..:.........|...:.||.|
  Fly   399 AT----------GASGKSGEDSGTPIVWPAWVYCTRYSDRPSSGRSPRARKPKKPATSSSAAGGG 453

  Fly   508 HDDSLNEDGIEEDIDDVDDADGSGGGDANGSDGLPNKKRKRRVLFTKAQTYELERRFRQQRYLSA 572
                  ..|:|:             |:|....|:|..||. |..|:..|...|:..|.:.|||:.
  Fly   454 ------GGGVEK-------------GEAADGGGVPEDKRP-RTAFSGTQLARLKHEFNENRYLTE 498

  Fly   573 PEREHLASLIRLTPTQVKIWFQNHRYKTKRAQNEKG-------YEGHPGLLHGHATHP 623
            ..|:.|:..:.|...|:||||||.|.|.|::...|.       .:|    |:.|:|.|
  Fly   499 KRRQQLSGELGLNEAQIKIWFQNKRAKLKKSSGTKNPLALQLMAQG----LYNHSTIP 552

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
vnd	NP_476786.2	Homeodomain	546..602	CDD:459649	21/55 (38%)
inv	NP_523699.3	Homeodomain	472..528	CDD:459649	22/56 (39%)
		Engrail_1_C_sig	529..554	CDD:431338	6/28 (21%)