Protein Alignment vnd and HOXC6

DIOPT Version :10

• Sequence 1: NP_476786.2
• Gene: vnd / 31003
• FlyBaseID: FBgn0261930
• Length: 723
• Species: Drosophila melanogaster
• Sequence 2: NP_004494.1
• Gene: HOXC6 / 3223
• HGNCID: 5128
• Length: 235
• Species: Homo sapiens
• Alignment Length: 265
• Identity: 65/265 - (24%)
• Similarity: 94/265 - (35%)
• Gaps: 80/265 - (30%)

  Fly   351 NAAAAAAVAAGQ-YLPNLPKNFPGSFGDEMSSYHHMAQTMLQH-SGRSAWIKENELYGTQQPASP 413
            |.:.:..:|.|| .|||:..|             ..|...::| |...|.:.:|.:|.|  |...
Human     7 NPSLSCHLAGGQDVLPNVALN-------------STAYDPVRHFSTYGAAVAQNRIYST--PFYS 56

  Fly   414 DSTSPVTSEVSYTYIGSNCQTSPALSGDYKSYSRSADSDALSVGDALHTLHGSSGNGSAGGAPTA 478
            ...:.|.|.....|             ||.|.|...:.|.||
Human    57 PQENVVFSSSRGPY-------------DYGSNSFYQEKDMLS----------------------- 85

  Fly   479 HALHNNNNNTTNNNNHSLKAEGINGAGSGHDDSLNEDGIEEDIDDVDDAD--------GSGGGDA 535
                |...||..:|..:..|:          |..:|.|.....|......        .|..|..
Human    86 ----NCRQNTLGHNTQTSIAQ----------DFSSEQGRTAPQDQKASIQIYPWMQRMNSHSGVG 136

  Fly   536 NGSDGLPNKKRKRRVLFTKAQTYELERRFRQQRYLSAPEREHLASLIRLTPTQVKIWFQNHRYKT 600
            .|:|     :|:.|.::::.||.|||:.|...|||:...|..:|:.:.||..|:||||||.|.|.
Human   137 YGAD-----RRRGRQIYSRYQTLELEKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMKW 196

  Fly   601 KRAQN 605
            |:..|
Human   197 KKESN 201

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
vnd	NP_476786.2	Homeodomain	546..602	CDD:459649	24/55 (44%)
HOXC6	NP_004494.1	Antp-type hexapeptide	122..127		0/4 (0%)
		Homeodomain	142..198	CDD:459649	24/55 (44%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	200..235		1/2 (50%)