Protein Alignment vnd and HOXB6

DIOPT Version :10

• Sequence 1: NP_476786.2
• Gene: vnd / 31003
• FlyBaseID: FBgn0261930
• Length: 723
• Species: Drosophila melanogaster
• Sequence 2: XP_011523029.1
• Gene: HOXB6 / 3216
• HGNCID: 5117
• Length: 288
• Species: Homo sapiens
• Alignment Length: 280
• Identity: 68/280 - (24%)
• Similarity: 103/280 - (36%)
• Gaps: 69/280 - (24%)

  Fly   372 PGSFGDEMSSYHHMAQ-----TMLQHSGRSAWIKENELYGTQQ---------PASP--------- 413
            |||..:......|..:     |..|..|.:|..:.:  |.|||         |.:|
Human     8 PGSLPENAQVSRHSRRREPRSTGRQFCGFNAARRSD--YKTQQIINPAEQQRPRAPPLPMSSYFV 70

  Fly   414 DSTSPVT-SEVSYTYIGSNCQTSPALSGDYKS--------YSRSADSDALSVGDALHTLHGSSGN 469
            :||.||| :....:::|.    .|..|..|..        |......|.   |.|..:.:..:|.
Human    71 NSTFPVTLASGQESFLGQ----LPLYSSGYADPLRHYPAPYGPGPGQDK---GFATSSYYPPAGG 128

  Fly   470 GSAGGAP----TAHALHNNNNNTTNNNNHSLKAEGINGAGSG---HDDSLNEDGIEED--IDDVD 525
            |....||    .|.|.:....:          |..::||...   |.:....|..::.  ..:.:
Human   129 GYGRAAPCDYGPAPAFYREKES----------ACALSGADEQPPFHPEPRKSDCAQDKSVFGETE 183

  Fly   526 DADGSGG--------GDANGSDGLPNKKRKRRVLFTKAQTYELERRFRQQRYLSAPEREHLASLI 582
            :...|..        ...|.|...|:.:|.|:. :|:.||.|||:.|...|||:...|..:|..:
Human   184 EQKCSTPVYPWMQRMNSCNSSSFGPSGRRGRQT-YTRYQTLELEKEFHYNRYLTRRRRIEIAHAL 247

  Fly   583 RLTPTQVKIWFQNHRYKTKR 602
            .||..|:||||||.|.|.|:
Human   248 CLTERQIKIWFQNRRMKWKK 267

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
vnd	NP_476786.2	Homeodomain	546..602	CDD:459649	25/55 (45%)
HOXB6	XP_011523029.1	Homeodomain	211..267	CDD:459649	25/56 (45%)