Protein Alignment vnd and HOXB5

DIOPT Version :10

• Sequence 1: NP_476786.2
• Gene: vnd / 31003
• FlyBaseID: FBgn0261930
• Length: 723
• Species: Drosophila melanogaster
• Sequence 2: NP_002138.1
• Gene: HOXB5 / 3215
• HGNCID: 5116
• Length: 269
• Species: Homo sapiens
• Alignment Length: 262
• Identity: 67/262 - (25%)
• Similarity: 108/262 - (41%)
• Gaps: 39/262 - (14%)

  Fly   360 AGQYLPNLPK----NFPGSFGDEMSSYHHMAQTMLQHSGRSAWIKENELYGTQQPASPDSTSPVT 420
            :|:| ||.|.    |: ||......||...|   ..|:|.         ||........|.:..:
Human    10 SGRY-PNGPDYQLLNY-GSGSSLSGSYRDPA---AMHTGS---------YGYNYNGMDLSVNRSS 60

  Fly   421 SEVS-YTYIGSNCQTSPALSGDYKSYSRSADSDALSVGDALHTLHGSS-GNGSAGGAPTAHALH- 482
            :..| :..:|.:.:..||.:.:.: :.::|.|.:||..::|...:|.| |...:..:|:..|..
Human    61 ASSSHFGAVGESSRAFPAPAQEPR-FRQAASSCSLSSPESLPCTNGDSHGAKPSASSPSDQATSA 124

  Fly   483 NNNNNTTNNNNHSLKAEGINGAGSGHDDSLNEDGIEEDIDDVDDADGSG------------GGDA 535
            :::.|.|..:..|..:|....|......||.....|.........:|..            ..|.
Human   125 SSSANFTEIDEASASSEPEEAASQLSSPSLARAQPEPMATSTAAPEGQTPQIFPWMRKLHISHDM 189

  Fly   536 NGSDGLPNKKRKRRVLFTKAQTYELERRFRQQRYLSAPEREHLASLIRLTPTQVKIWFQNHRYKT 600
            .|.||     ::.|..:|:.||.|||:.|...|||:...|..:|..:.|:..|:||||||.|.|.
Human   190 TGPDG-----KRARTAYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLSERQIKIWFQNRRMKW 249

  Fly   601 KR 602
            |:
Human   250 KK 251

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
vnd	NP_476786.2	Homeodomain	546..602	CDD:459649	23/55 (42%)
HOXB5	NP_002138.1	PRK07003	<67..>171	CDD:235906	21/104 (20%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	77..173		21/96 (22%)
		Antp-type hexapeptide	176..181		0/4 (0%)
		Homeodomain	195..251	CDD:459649	23/55 (42%)