Protein Alignment vnd and HOXA5

DIOPT Version :10

• Sequence 1: NP_476786.2
• Gene: vnd / 31003
• FlyBaseID: FBgn0261930
• Length: 723
• Species: Drosophila melanogaster
• Sequence 2: NP_061975.2
• Gene: HOXA5 / 3202
• HGNCID: 5106
• Length: 270
• Species: Homo sapiens
• Alignment Length: 283
• Identity: 66/283 - (23%)
• Similarity: 104/283 - (36%)
• Gaps: 82/283 - (28%)

  Fly   361 GQYLPNLPKNFPGSFGDEMSSYHHMAQTMLQHSGRSAWIKENELYGTQQPASPDSTSPVTSEVSY 425
            |:| ||.|.....::||..|.......:...||||         ||                  |
Human    11 GRY-PNGPDYQLHNYGDHSSVSEQFRDSASMHSGR---------YG------------------Y 47

  Fly   426 TYIGSNCQTSPALSGDY------KSYSRSADSDALSVGDALHTLHGSSGN---------GSAGGA 475
            .|.|.:.....:.||.:      :||:.||.:   :..:..::...:|.:         .:...:
Human    48 GYNGMDLSVGRSGSGHFGSGERARSYAASASA---APAEPRYSQPATSTHSPQPDPLPCSAVAPS 109

  Fly   476 PTAHALHNNNNNTTNNNNHSLKA--------EGINGAGSGHDD---SLNEDGIEEDIDDVDDA-- 527
            |.:.:.|...|:.:|::..|..|        ||:..|....:|   |..:...:.:......|
Human   110 PGSDSHHGGKNSLSNSSGASADAGSTHISSREGVGTASGAEEDAPASSEQASAQSEPSPAPPAQP 174

  Fly   528 -------------DGSGGGDANGSDGLPNKKRKRRVLFTKAQTYELERRFRQQRYLSAPEREHLA 579
                         |..||         |..|| .|..:|:.||.|||:.|...|||:...|..:|
Human   175 QIYPWMRKLHISHDNIGG---------PEGKR-ARTAYTRYQTLELEKEFHFNRYLTRRRRIEIA 229

  Fly   580 SLIRLTPTQVKIWFQNHRYKTKR 602
            ..:.|:..|:||||||.|.|.|:
Human   230 HALCLSERQIKIWFQNRRMKWKK 252

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
vnd	NP_476786.2	Homeodomain	546..602	CDD:459649	24/55 (44%)
HOXA5	NP_061975.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	75..175		15/102 (15%)
		Antp-type hexapeptide	176..181		0/4 (0%)
		Homeodomain	196..252	CDD:459649	25/56 (45%)