Protein Alignment vnd and NKX2-8

DIOPT Version :10

• Sequence 1: NP_476786.2
• Gene: vnd / 31003
• FlyBaseID: FBgn0261930
• Length: 723
• Species: Drosophila melanogaster
• Sequence 2: NP_055175.2
• Gene: NKX2-8 / 26257
• HGNCID: 16364
• Length: 239
• Species: Homo sapiens
• Alignment Length: 200
• Identity: 95/200 - (47%)
• Similarity: 109/200 - (54%)
• Gaps: 28/200 - (14%)

  Fly   507 GHDDSLNEDGIEEDIDDVDD----ADGSGGGDANGSDGLPNKKRKRRVLFTKAQTYELERRFRQQ 567
            ||..|.:|..:|....|...    ...|.|.||       .|::||||||:||||.|||||||||
Human    49 GHYPSSDESSLETSPPDSSQRPSARPASPGSDA-------EKRKKRRVLFSKAQTLELERRFRQQ 106

  Fly   568 RYLSAPEREHLASLIRLTPTQVKIWFQNHRYKTKRAQNEKGYEGHPGLLHGHATHPHHPSALPSP 632
            |||||||||.||||:|||||||||||||||||.|||: ..|....|.|......|. .|..|
Human   107 RYLSAPEREQLASLLRLTPTQVKIWFQNHRYKLKRAR-APGAAESPDLAASAELHA-APGLL--- 166

  Fly   633 RRVAVPVLVRNGKPCLGDSSKLGADCVSVSSATATAMQNAAAHHL---------VALNGAAAYQH 688
            |||.||||||:|:||.|..   |.:..:.::........|||..|         .||....||||
Human   167 RRVVVPVLVRDGQPCGGGG---GGEVGTAAAQEKCGAPPAAACPLPGYPAFGPGSALGLFPAYQH 228

  Fly   689 AAAAA 693
            .|:.|
Human   229 LASPA 233

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
vnd	NP_476786.2	Homeodomain	546..602	CDD:459649	49/55 (89%)
NKX2-8	NP_055175.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..87		11/44 (25%)
		Homeodomain	85..141	CDD:459649	49/55 (89%)