Protein Alignment vnd and Nkx2-1

DIOPT Version :9

• Sequence 1: NP_476786.2
• Gene: vnd / 31003
• FlyBaseID: FBgn0261930
• Length: 723
• Species: Drosophila melanogaster
• Sequence 2: XP_006240178.1
• Gene: Nkx2-1 / 25628
• RGDID: 3866
• Length: 423
• Species: Rattus norvegicus
• Alignment Length: 548
• Identity: 156/548 - (28%)
• Similarity: 195/548 - (35%)
• Gaps: 199/548 - (36%)

  Fly   190 AKVPSSQRSGFHISDILNLEGSELKNAAAAAAAAAHHGSDLSHHSASESTSGHRGQGSHTSP--- 251
            ||..:.|....|.|.:.....:.|:.....:|.:......:|              ..||:|
  Rat    14 AKTNARQPPSLHSSQLRRTRSTPLRVHPTRSALSRRRIMSMS--------------PKHTTPFSV 64

  Fly   252 -SALSPTPAGVSADEHHNGSG-TGGGAGEADHHSTTEHHAPPSHPQQQHPHHQQHHHPHLLLPQQ 314
             ..|||      .:|.:...| .|||.|...........|||:...|||
  Rat    65 SDILSP------LEESYKKVGMEGGGLGAPLAAYRQGQAAPPAAAMQQH---------------- 107

  Fly   315 HHQQAVAPLPLAHHQSGEAQSHAHANAAAAHLLASHNAAAAAAVAAGQYLPNLPKNFPGSFGD-- 377
                     .:.||  |...:..|..||....| ||:       |.|.|.       .|:.|:
  Rat   108 ---------AVGHH--GAVTAAYHMTAAGVPQL-SHS-------AVGGYC-------NGNLGNVS 146

  Fly   378 EMSSYHHMAQTMLQHSGRSAWIKENELYGTQQPASPDSTSPVTSEVSYTYIGSNCQTSPALSGDY 442
            |:..|.   .||...:....|      ||    |:||...|..|.    ::|
  Rat   147 ELPPYQ---DTMRNSASGPGW------YG----ANPDPRFPAISR----FMG------------- 181

  Fly   443 KSYSRSADSDALSVGDALHTLHGSSGNGSAGGAPTAHALHNNNNNTTNNNNHSLKAEGINGAGSG 507
                                                                  .|.|:|.:|.|
  Rat   182 ------------------------------------------------------PASGMNMSGMG 192

  Fly   508 HDDSLNEDGIEEDIDDVDDADGSGGGDANGSDGLPN-KKRKRRVLFTKAQTYELERRFRQQRYLS 571
                    |:           ||.|..:.....||: .:|||||||::||.|||||||:||:|||
  Rat   193 --------GL-----------GSLGDVSKNMAPLPSAPRRKRRVLFSQAQVYELERRFKQQKYLS 238

  Fly   572 APEREHLASLIRLTPTQVKIWFQNHRYKTKRAQNEKGYE-------GHPGLLHGHATHPHHPSA- 628
            |||||||||:|.||||||||||||||||.||...:|..:       |..|...|.|..|....|
  Rat   239 APEREHLASMIHLTPTQVKIWFQNHRYKMKRQAKDKAAQQQLQQDSGGGGGGGGGAGCPQQQQAQ 303

  Fly   629 LPSPRRVAVPVLVRNGKPCLGDSSKLGADCVSVSSATATAMQNAAAHHLVALNGAAAYQHAAAA- 692
            ..|||||||||||::||||     :.||.....:|....|.|.|...       |.|.|.||||
  Rat   304 QQSPRRVAVPVLVKDGKPC-----QAGAPAPGAASLQGHAQQQAQQQ-------AQAAQAAAAAI 356

  Fly   693 -----AAGLHAHAHAHAHAHGHGHPHAH 715
                 .|||.||......:.|.....||
  Rat   357 SVGSGGAGLGAHPGHQPGSAGQSPDLAH 384

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
vnd	NP_476786.2	Homeobox	548..601	CDD:278475	45/52 (87%)
Nkx2-1	XP_006240178.1	Homeobox	215..268	CDD:278475	45/52 (87%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0842
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X524
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.810