Protein Alignment vnd and Nkx2-1

DIOPT Version :9

• Sequence 1: NP_476786.2
• Gene: vnd / 31003
• FlyBaseID: FBgn0261930
• Length: 723
• Species: Drosophila melanogaster
• Sequence 2: XP_011242403.1
• Gene: Nkx2-1 / 21869
• MGIID: 108067
• Length: 423
• Species: Mus musculus
• Alignment Length: 546
• Identity: 156/546 - (28%)
• Similarity: 195/546 - (35%)
• Gaps: 195/546 - (35%)

  Fly   190 AKVPSSQRSGFHISDILNLEGSELKNAAAAAAAAAHHGSDLSHHSASESTSGHRGQGSHTSP--- 251
            ||..:.|....|.|.:.....:.|:.....:|.:......:|              ..||:|
Mouse    14 AKTNARQPPSLHSSQLRRTRSTPLRVHPTRSALSRRRIMSMS--------------PKHTTPFSV 64

  Fly   252 -SALSPTPAGVSADEHHNGSG-TGGGAGEADHHSTTEHHAPPSHPQQQHPHHQQHHHPHLLLPQQ 314
             ..|||      .:|.:...| .|||.|...........|||:...|||
Mouse    65 SDILSP------LEESYKKVGMEGGGLGAPLAAYRQGQAAPPAAAMQQH---------------- 107

  Fly   315 HHQQAVAPLPLAHHQSGEAQSHAHANAAAAHLLASHNAAAAAAVAAGQYLPNLPKNFPGSFGDEM 379
                     .:.||  |...:..|..||....| ||:       |.|.|.       .|:.|: |
Mouse   108 ---------AVGHH--GAVTAAYHMTAAGVPQL-SHS-------AVGGYC-------NGNLGN-M 145

  Fly   380 SSYHHMAQTMLQHSGRSAWIKENELYGTQQPASPDSTSPVTSEVSYTYIGSNCQTSPALSGDYKS 444
            |.......||...:....|      ||    |:||...|..|.    ::|
Mouse   146 SELPPYQDTMRNSASGPGW------YG----ANPDPRFPAISR----FMG--------------- 181

  Fly   445 YSRSADSDALSVGDALHTLHGSSGNGSAGGAPTAHALHNNNNNTTNNNNHSLKAEGINGAGSGHD 509
                                                                .|.|:|.:|.|
Mouse   182 ----------------------------------------------------PASGMNMSGMG-- 192

  Fly   510 DSLNEDGIEEDIDDVDDADGSGGGDANGSDGLPN-KKRKRRVLFTKAQTYELERRFRQQRYLSAP 573
                  |:           ||.|..:.....||: .:|||||||::||.|||||||:||:|||||
Mouse   193 ------GL-----------GSLGDVSKNMAPLPSAPRRKRRVLFSQAQVYELERRFKQQKYLSAP 240

  Fly   574 EREHLASLIRLTPTQVKIWFQNHRYKTKRAQNEKGYE-------GHPGLLHGHATHPHHPSA-LP 630
            |||||||:|.||||||||||||||||.||...:|..:       |..|...|.|..|....| ..
Mouse   241 EREHLASMIHLTPTQVKIWFQNHRYKMKRQAKDKAAQQQLQQDSGGGGGGGGGAGCPQQQQAQQQ 305

  Fly   631 SPRRVAVPVLVRNGKPCLGDSSKLGADCVSVSSATATAMQNAAAHHLVALNGAAAYQHAAAA--- 692
            |||||||||||::||||     :.||.....:|..:.|.|.|...       |.|.|.||||
Mouse   306 SPRRVAVPVLVKDGKPC-----QAGAPAPGAASLQSHAQQQAQQQ-------AQAAQAAAAAISV 358

  Fly   693 ---AAGLHAHAHAHAHAHGHGHPHAH 715
               .|||.||......:.|.....||
Mouse   359 GSGGAGLGAHPGHQPGSAGQSPDLAH 384

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
vnd	NP_476786.2	Homeobox	548..601	CDD:278475	45/52 (87%)
Nkx2-1	XP_011242403.1	Homeobox	215..269	CDD:395001	45/53 (85%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0842
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X524
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.810