Protein Alignment vnd and EVX1

DIOPT Version :10

• Sequence 1: NP_476786.2
• Gene: vnd / 31003
• FlyBaseID: FBgn0261930
• Length: 723
• Species: Drosophila melanogaster
• Sequence 2: NP_001980.1
• Gene: EVX1 / 2128
• HGNCID: 3506
• Length: 407
• Species: Homo sapiens
• Alignment Length: 359
• Identity: 83/359 - (23%)
• Similarity: 123/359 - (34%)
• Gaps: 135/359 - (37%)

  Fly   402 NELYGTQQPASPDSTSPVTSEVSYTYIGSNCQTSPALSGDYKSYSRSADSDALSVGDALHTLHGS 466
            :.|.|..||:|.|:.|....|:..: ...:|.|..|   :|: :|:.:.|:||.
Human   102 DSLSGQGQPSSSDTESDFYEEIEVS-CTPDCATGNA---EYQ-HSKGSGSEALV----------- 150

  Fly   467 SGNGSAGGAPTAHALHNNNNNTTNNNNHSLKAEGINGAGSGHDDSLNEDGIEEDIDDVDDADGSG 531
                   |:|      |..:.|..:|.                                   |||
Human   151 -------GSP------NGGSETPKSNG-----------------------------------GSG 167

  Fly   532 GGDANG--SDGLPNKKRKRRVLFTKAQTYELERRFRQQRYLSAPEREHLASLIRLTPTQVKIWFQ 594
            ||.:.|  :....::.|:.|..||:.|...||:.|.::.|:|.|.|..||:.:.|..|.:|:|||
Human   168 GGGSQGTLACSASDQMRRYRTAFTREQIARLEKEFYRENYVSRPRRCELAAALNLPETTIKVWFQ 232

  Fly   595 NHRYKTKRAQNEKGYEGHPG------LLHGHAT------HPHHPSALPSPRRVAVPVLVRNGKPC 647
            |.|.|.||.:....:. ||.      .:..||.      :| .||.||.|.
Human   233 NRRMKDKRQRLAMTWP-HPADPAFYTYMMSHAAAAGGLPYP-FPSHLPLPY-------------- 281

  Fly   648 LGDSSKLGADCVSVSSATATAMQNA---------------------AAHHLVALNGAAAYQHAAA 691
               .|.:|....|.:||.|:....:                     |..|.....|.|   |...
Human   282 ---YSPVGLGAASAASAAASPFSGSLRPLDTFRVLSQPYPRPELLCAFRHPPLYPGPA---HGLG 340

  Fly   692 AAAG-----LHAHAHAHAHAHGHGHPHAHAQRAA 720
            |:||     |..|:         |..:..|.|||
Human   341 ASAGGPCSCLACHS---------GPANGLAPRAA 365

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
vnd	NP_476786.2	Homeodomain	546..602	CDD:459649	23/55 (42%)
EVX1	NP_001980.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	29..120		7/17 (41%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	137..179		16/101 (16%)
		Homeodomain	184..240	CDD:459649	23/55 (42%)