Protein Alignment vnd and Nkx1-2

DIOPT Version :10

• Sequence 1: NP_476786.2
• Gene: vnd / 31003
• FlyBaseID: FBgn0261930
• Length: 723
• Species: Drosophila melanogaster
• Sequence 2: NP_033149.1
• Gene: Nkx1-2 / 20231
• MGIID: 104806
• Length: 305
• Species: Mus musculus
• Alignment Length: 217
• Identity: 66/217 - (30%)
• Similarity: 85/217 - (39%)
• Gaps: 73/217 - (33%)

  Fly   502 NGAGSGHDDSLNEDGIE-EDIDDVDDA-------------DGSG-------GGDANGSDGLP--- 542
            :..|.|.|.....:|.| |:.::.:||             :||.       |.:.:|::|||
Mouse    72 DAVGRGIDPGSPVEGSEAEEEEEAEDAGRAHQPERWQGVHEGSPEARAVAVGTEESGAEGLPASP 136

  Fly   543 -----------------NKKRKRRVLFTKAQTYELERRFRQQRYLSAPEREHLASLIRLTPTQVK 590
                             .|.|:.|..||..|...||.:||..||||..||.:||..:.||.||||
Mouse   137 GSPGSPRPRRRRAESSCAKPRRARTAFTYEQLVALENKFRATRYLSVCERLNLALSLSLTETQVK 201

  Fly   591 IWFQNHRYKTKRAQN-------EKG----YEGHPGLL-------HGHATHPHHPSALP---SPRR 634
            |||||.|.|.|: ||       :.|    ..|.||.:       .|.:..|..|.|||   .|..
Mouse   202 IWFQNRRTKWKK-QNPGADGAVQAGGGAPQPGTPGAVAGGGGSATGSSPGPPVPGALPYQTFPTY 265

  Fly   635 VAVPVL----------VRNGKP 646
            .|..||          ..||.|
Mouse   266 PATNVLFPAASFPLTTAANGSP 287

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
vnd	NP_476786.2	Homeodomain	546..602	CDD:459649	30/55 (55%)
Nkx1-2	NP_033149.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	51..158		16/85 (19%)
		Homeodomain	157..213	CDD:459649	30/55 (55%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	210..257		11/47 (23%)