Protein Alignment vnd and Nkx2-2

DIOPT Version :9

• Sequence 1: NP_476786.2
• Gene: vnd / 31003
• FlyBaseID: FBgn0261930
• Length: 723
• Species: Drosophila melanogaster
• Sequence 2: NP_035049.1
• Gene: Nkx2-2 / 18088
• MGIID: 97347
• Length: 273
• Species: Mus musculus
• Alignment Length: 280
• Identity: 115/280 - (41%)
• Similarity: 136/280 - (48%)
• Gaps: 75/280 - (26%)

  Fly   465 GSSGNGSAGGA---PTAHALHNNNNN-------TTNNNNHSLKAEGINGAGSGHDDSLN--EDGI 517
            |..|.|:....   |.....:::::|       :|....:||  .|:..:....|.|..  |...
Mouse    46 GPLGQGALDAVQSLPLKSPFYDSSDNPYTRWLASTEGLQYSL--HGLAASAPPQDSSSKSPEPSA 108

  Fly   518 EEDIDDVDDADGSGGGDANGSDGLPNKKRKRRVLFTKAQTYELERRFRQQRYLSAPEREHLASLI 582
            :|..|:..:..| |||||       .|||||||||:|||||||||||||||||||||||||||||
Mouse   109 DESPDNDKETQG-GGGDA-------GKKRKRRVLFSKAQTYELERRFRQQRYLSAPEREHLASLI 165

  Fly   583 RLTPTQVKIWFQNHRYKTKRAQNEKGYEGHPGLLHGHATHPHHPSALPSPRRVAVPVLVRNGKPC 647
            |||||||||||||||||.|||:.|||.|..|               ||||||||||||||:||||
Mouse   166 RLTPTQVKIWFQNHRYKMKRARAEKGMEVTP---------------LPSPRRVAVPVLVRDGKPC 215

  Fly   648 LGDSSKLGADCVSVSSATATAMQNAAAHHLVALNGAAAYQHAAAAAAGLHAHAHAHAHAHGH--- 709
                                       |.|.|.:.|||...|....:...|.:..|...:..
Mouse   216 ---------------------------HALKAQDLAAATFQAGIPFSAYSAQSLQHMQYNAQYSS 253

  Fly   710 --------GHPHAHAQRAAW 721
                    .||...||:..|
Mouse   254 ASTPQYPTAHPLVQAQQWTW 273

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
vnd	NP_476786.2	Homeobox	548..601	CDD:278475	51/52 (98%)
Nkx2-2	NP_035049.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..56		3/9 (33%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	91..131		14/47 (30%)
		Homeobox	131..185	CDD:395001	51/53 (96%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	115	1.000	Domainoid score	I6029
eggNOG	1	0.900	-	-		E2759_KOG0842
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0002404
OrthoInspector	1	1.000	-	-		oto92721
orthoMCL	1	0.900	-	-		OOG6_108087
Panther	1	1.100	-	-	O	PTHR24340
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2570
SonicParanoid	1	1.000	-	-		X524
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	11	10.800