Protein Alignment vnd and DLX5

DIOPT Version :10

• Sequence 1: NP_476786.2
• Gene: vnd / 31003
• FlyBaseID: FBgn0261930
• Length: 723
• Species: Drosophila melanogaster
• Sequence 2: NP_005212.1
• Gene: DLX5 / 1749
• HGNCID: 2918
• Length: 289
• Species: Homo sapiens
• Alignment Length: 304
• Identity: 83/304 - (27%)
• Similarity: 129/304 - (42%)
• Gaps: 78/304 - (25%)

  Fly   439 SGDYKS-YSRSADSDALSVGDALH-------TLHGSSGNGSAGGAPTAHALHNNNNNTTNN---- 491
            |||::: :..||         |:|       ||..||...|...:||..|.|...:.|:.:
Human    14 SGDFQAPFQTSA---------AMHHPSQESPTLPESSATDSDYYSPTGGAPHGYCSPTSASYGKA 69

  Fly   492 -NNHSLKAEGING-AGS---------GHDDSLNEDG------------IEEDIDDVDDADGSGGG 533
             |.:..:..|:|| |||         .:..|.::.|            .|:::.:         .
Human    70 LNPYQYQYHGVNGSAGSYPAKAYADYSYASSYHQYGGAYNRVPSATNQPEKEVTE---------P 125

  Fly   534 DANGSDGLPNKKRKRRVLFTKAQTYELERRFRQQRYLSAPEREHLASLIRLTPTQVKIWFQNHRY 598
            :....:|.|.|.||.|.:::..|...|:|||::.:||:.|||..||:.:.||.|||||||||.|.
Human   126 EVRMVNGKPKKVRKPRTIYSSFQLAALQRRFQKTQYLALPERAELAASLGLTQTQVKIWFQNKRS 190

  Fly   599 KTKRAQNEKGYEGHPGLLHGHATHPHHPSALPSPRRVAVPVLVRNGKPCLGDSSKL-----GADC 658
            |.|:..  |..|..|    .|:.....|.|..||:..||      .:| .|.|..|     ....
Human   191 KIKKIM--KNGEMPP----EHSPSSSDPMACNSPQSPAV------WEP-QGSSRSLSHHPHAHPP 242

  Fly   659 VSVSSATATAMQNAAAHHLVALNGAAAY-------QHAAAAAAG 695
            .|..|..::.::|:|:.:..|.:...::       ||..|.|:|
Human   243 TSNQSPASSYLENSASWYTSAASSINSHLPPPGSLQHPLALASG 286

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
vnd	NP_476786.2	Homeodomain	546..602	CDD:459649	28/55 (51%)
DLX5	NP_005212.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..49		12/43 (28%)
		DLL_N	32..118	CDD:463567	19/85 (22%)
		Homeodomain	138..194	CDD:459649	28/55 (51%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	198..251		15/63 (24%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	270..289		5/17 (29%)