Protein Alignment vnd and NKX2-3

DIOPT Version :9

• Sequence 1: NP_476786.2
• Gene: vnd / 31003
• FlyBaseID: FBgn0261930
• Length: 723
• Species: Drosophila melanogaster
• Sequence 2: NP_660328.2
• Gene: NKX2-3 / 159296
• HGNCID: 7836
• Length: 364
• Species: Homo sapiens
• Alignment Length: 326
• Identity: 111/326 - (34%)
• Similarity: 161/326 - (49%)
• Gaps: 62/326 - (19%)

  Fly   417 SPVTS-----------EVSYTYI-GSNCQ--------TSPAL--SGDYKSYSRSADSDALSVGDA 459
            |||||           |..:.:. |::.|        ::|.:  :.:...:|...:.|....|:.
Human     5 SPVTSTPFSVKDILNLEQQHQHFHGAHLQADLEHHFHSAPCMLAAAEGTQFSDGGEEDEEDEGEK 69

  Fly   460 ---LHTLHGSSGNGSAGGAPTAHALHNNNNNTTNNNNHSLKAEGINGAGSGHDDSLNEDGIEEDI 521
               |::|..:.|:|.:|..|..:......::.:....|..:.|.:      .|.|.....:::.:
Human    70 LSYLNSLAAADGHGDSGLCPQGYVHTVLRDSCSEPKEHEEEPEVV------RDRSQKSCQLKKSL 128

  Fly   522 DDVDDADGSGGGDANGSDGLPNKKRKRRVLFTKAQTYELERRFRQQRYLSAPEREHLASLIRLTP 586
            :...|...:    .......|..:||.||||::||.:||||||:|||||||||||||||.::||.
Human   129 ETAGDCKAA----EESERPKPRSRRKPRVLFSQAQVFELERRFKQQRYLSAPEREHLASSLKLTS 189

  Fly   587 TQVKIWFQNHRYKTKRAQNEKGYEGHPGLLHGHATHPHHPSALPSPRRVAVPVLVRNGKPCLGDS 651
            |||||||||.|||.||.:.:|..|     |..||..       |.|||||||||||:||||:..|
Human   190 TQVKIWFQNRRYKCKRQRQDKSLE-----LGAHAPP-------PPPRRVAVPVLVRDGKPCVTPS 242

  Fly   652 SK-------LGADCVSVSSATATAMQNAAAHHLVALNGAAAYQHAAAAAAGLHAHAHAHAHAHGH 709
            ::       :||...|.:|..|....|:||        |||...||||||..::.::..|:..|.
Human   243 AQAYGAPYSVGASAYSYNSFPAYGYGNSAA--------AAAAAAAAAAAAAAYSSSYGCAYPAGG 299

  Fly   710 G 710
            |
Human   300 G 300

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
vnd	NP_476786.2	Homeobox	548..601	CDD:278475	41/52 (79%)
NKX2-3	NP_660328.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	132..153		4/24 (17%)
		HOX	148..204	CDD:197696	43/55 (78%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	46	1.000	Domainoid score	I12127
eggNOG	1	0.900	-	-		E2759_KOG0842
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.810