Protein Alignment vnd and NKX6-3

DIOPT Version :10

• Sequence 1: NP_476786.2
• Gene: vnd / 31003
• FlyBaseID: FBgn0261930
• Length: 723
• Species: Drosophila melanogaster
• Sequence 2: NP_001351770.1
• Gene: NKX6-3 / 157848
• HGNCID: 26328
• Length: 265
• Species: Homo sapiens
• Alignment Length: 232
• Identity: 59/232 - (25%)
• Similarity: 90/232 - (38%)
• Gaps: 67/232 - (28%)

  Fly   401 ENELYGT----QQPAS--PDSTSPVTSEVSYTYIGSNCQTSPALSGDYKSYSRSADSDALSVGDA 459
            |:.|.||    ..|.:  |:..:||            ||                    .||.::
Human     2 ESNLQGTFLLNNTPLAQFPEMKAPV------------CQ--------------------YSVQNS 34

  Fly   460 LHTLHGSSGNGSAGGAPTAHALHNNNNNTTNNNNHSLKAEGINGAGSGHDDSLNEDGI--EEDID 522
            .:.| ...|.|....|.|.|.:.:..:......|:||.:...:.||.|   .|:..|:  ...:.
Human    35 FYKL-SPPGLGPQLAAGTPHGITDILSRPVAAPNNSLLSGYPHVAGFG---GLSSQGVYYSPQVG 95

  Fly   523 DVDDA-----------------DGSGGGDANG-----SDGLPNKKRKRRVLFTKAQTYELERRFR 565
            :...|                 |..||...:.     ||.: :||:..|..||..|.:.||:.|.
Human    96 NFSKAGNEYPTRTRNCWADTGQDWRGGRQCSNTPDPLSDSI-HKKKHTRPTFTGHQIFALEKTFE 159

  Fly   566 QQRYLSAPEREHLASLIRLTPTQVKIWFQNHRYKTKR 602
            |.:||:.|||..||..:.:|.:|||:||||.|.|.::
Human   160 QTKYLAGPERARLAYSLGMTESQVKVWFQNRRTKWRK 196

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
vnd	NP_476786.2	Homeodomain	546..602	CDD:459649	25/55 (45%)
NKX6-3	NP_001351770.1	Homeodomain	138..196	CDD:459649	27/57 (47%)