Protein Alignment vnd and Nkx6-2

DIOPT Version :10

• Sequence 1: NP_476786.2
• Gene: vnd / 31003
• FlyBaseID: FBgn0261930
• Length: 723
• Species: Drosophila melanogaster
• Sequence 2: NP_899071.2
• Gene: Nkx6-2 / 14912
• MGIID: 1352738
• Length: 277
• Species: Mus musculus
• Alignment Length: 253
• Identity: 59/253 - (23%)
• Similarity: 88/253 - (34%)
• Gaps: 71/253 - (28%)

  Fly   370 NFPGSF---GDEMSSYHHMAQTMLQHSGRSAWIKENELYGTQQPASPDSTSPVTSEVSYTYIGSN 431
            |.||:|   ...:::.|:||:..                              ||...|...|..
Mouse     4 NRPGAFVLSSAPLAALHNMAEMK------------------------------TSLFPYALQGPA 38

  Fly   432 CQTSPALSGDYKSYSRSAD---SDALSVGDALHTLHGSSGNGSAGGAPTAHALHNNNNNTTNNNN 493
            ...:|||.      |..|.   .....:.|.|....|::|.|..|..|..:.|
Mouse    39 GFKTPALG------SLGAQLPLGTPHGISDILGRPVGAAGGGLLGSLPRLNGL------------ 85

  Fly   494 HSLKAEGI-----NGAGSGHDDSLNE---------DGIEEDIDDVDDADGSGGGDANGSDGLPNK 544
              ..:.|:     .....|:...|.|         .|:.:. ....|...:|...|.|......|
Mouse    86 --ASSAGVYFGPAAAVARGYPKPLAELPGRPPIFWPGVVQG-SPWRDPRLAGSAQAGGVLDKDGK 147

  Fly   545 KRKRRVLFTKAQTYELERRFRQQRYLSAPEREHLASLIRLTPTQVKIWFQNHRYKTKR 602
            |:..|..|:..|.:.||:.|.|.:||:.|||..||..:.:|.:|||:||||.|.|.::
Mouse   148 KKHSRPTFSGQQIFALEKTFEQTKYLAGPERARLAYSLGMTESQVKVWFQNRRTKWRK 205

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
vnd	NP_476786.2	Homeodomain	546..602	CDD:459649	24/55 (44%)
Nkx6-2	NP_899071.2	Homeodomain	147..205	CDD:459649	26/57 (46%)