Protein Alignment vnd and NKX2-5

DIOPT Version :9

• Sequence 1: NP_476786.2
• Gene: vnd / 31003
• FlyBaseID: FBgn0261930
• Length: 723
• Species: Drosophila melanogaster
• Sequence 2: NP_004378.1
• Gene: NKX2-5 / 1482
• HGNCID: 2488
• Length: 324
• Species: Homo sapiens
• Alignment Length: 175
• Identity: 78/175 - (44%)
• Similarity: 94/175 - (53%)
• Gaps: 48/175 - (27%)

  Fly   544 KKRKRRVLFTKAQTYELERRFRQQRYLSAPEREHLASLIRLTPTQVKIWFQNHRYKTKRAQNEKG 608
            ::||.||||::||.|||||||:||||||||||:.|||:::||.|||||||||.|||.||.:.::.
Human   137 RRRKPRVLFSQAQVYELERRFKQQRYLSAPERDQLASVLKLTSTQVKIWFQNRRYKCKRQRQDQT 201

  Fly   609 YE--GHPGLLHGHATHPHHPSALPSPRRVAVPVLVRNGKPCLGDSSKL----------------- 654
            .|  |.|            |...|..||:|||||||:||||||||:..
Human   202 LELVGLP------------PPPPPPARRIAVPVLVRDGKPCLGDSAPYAPAYGVGLNPYGYNAYP 254

  Fly   655 ------GADCVSVSSATATAMQNAAAHHLVALNGAAAYQHAAAAA 693
                  ||.|....|.||....           |.:..|.|.|||
Human   255 AYPGYGGAACSPGYSCTAAYPA-----------GPSPAQPATAAA 288

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
vnd	NP_476786.2	Homeobox	548..601	CDD:278475	40/52 (77%)
NKX2-5	NP_004378.1	Homeobox	145..194	CDD:278475	37/48 (77%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	46	1.000	Domainoid score	I12127
eggNOG	1	0.900	-	-		E2759_KOG0842
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0002404
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.810