Protein Alignment vnd and Evx2

DIOPT Version :10

• Sequence 1: NP_476786.2
• Gene: vnd / 31003
• FlyBaseID: FBgn0261930
• Length: 723
• Species: Drosophila melanogaster
• Sequence 2: NP_031993.1
• Gene: Evx2 / 14029
• MGIID: 95462
• Length: 475
• Species: Mus musculus
• Alignment Length: 416
• Identity: 106/416 - (25%)
• Similarity: 160/416 - (38%)
• Gaps: 109/416 - (26%)

  Fly   330 SGEAQSHAHANAAAAHLLASHNAAAAAAVAAGQYLPNLPKNFPGSFGDEMSSYHHMAQTM--LQH 392
            :|:..|....:|..|.|.|..|:...|.::  ..||:.|.:  |:.||..:.......|:  |||
Mouse    21 AGKRFSSLSDSAGGAVLEALENSQHPARLS--PRLPSAPLH--GALGDLPAKGKFEIDTLFNLQH 81

  Fly   393 SGRSAWIKENELYGTQQPASPDSTSPVTSEV---SYTYIGSNCQTSPALSG-------DYKSYSR 447
            ....:.:.......|:....|...|...:|.   |...:|.:...||:..|       :.|.|:.
Mouse    82 PSSESTVSSEIASATESRKKPSHYSEAAAEADMSSDVEVGCSALRSPSGLGAAPLKENNAKGYTE 146

  Fly   448 S---ADSDALSVGDALHTLHGSSGNGSAGGAPTAHALHNNNNNTTNNNNHSLKAEGINGAGSGHD 509
            |   |.:...:.|..|.:|||..|.|::|.|                      |.|.:|:|||.|
Mouse   147 SGSVAGTTTSASGSGLGSLHGGGGGGNSGAA----------------------ALGGSGSGSGAD 189

  Fly   510 DSLNEDGIEEDIDDVDDADGSGGGDANGSDGLPNKKRKRRVLFTKAQTYELERRFRQQRYLSAPE 574
                                              :.|:.|..||:.|...||:.|.::.|:|.|.
Mouse   190 ----------------------------------QVRRYRTAFTREQIARLEKEFYRENYVSRPR 220

  Fly   575 REHLASLIRLTPTQVKIWFQNHRYKTKRAQNEKGYEGHPG--------LLHGHATHPHHPSALPS 631
            |..||:.:.|..|.:|:||||.|.|.||.:....:. ||.        :.|..||     .:||.
Mouse   221 RCELAAALNLPETTIKVWFQNRRMKDKRQRLAMSWP-HPADPSFYTYMMTHAAAT-----GSLPY 279

  Fly   632 PRRVAVPVLVRNGKPCLGDSSKLGADCVS-----VSSATATAMQ-----NAAAHH------LVAL 680
            |....||:   :..|.:|.::...|...|     .||..||:::     .|.:|.      |.:.
Mouse   280 PFHSHVPL---HYYPHVGVTAAAAAAAASGAAAAASSPFATSIRPLDTFRALSHPYSRPELLCSF 341

  Fly   681 NGAAAYQHAAAAAAGLHAHAHAHAHA 706
            .....|| |.||||||::.|.|.|.|
Mouse   342 RHPGLYQ-APAAAAGLNSAASAAAAA 366

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
vnd	NP_476786.2	Homeodomain	546..602	CDD:459649	23/55 (42%)
Evx2	NP_031993.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	82..113		4/30 (13%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	155..189		15/55 (27%)
		Homeodomain	192..248	CDD:459649	23/55 (42%)