Protein Alignment vnd and NKX2-6

DIOPT Version :9

• Sequence 1: NP_476786.2
• Gene: vnd / 31003
• FlyBaseID: FBgn0261930
• Length: 723
• Species: Drosophila melanogaster
• Sequence 2: NP_001129743.2
• Gene: NKX2-6 / 137814
• HGNCID: 32940
• Length: 301
• Species: Homo sapiens
• Alignment Length: 284
• Identity: 104/284 - (36%)
• Similarity: 128/284 - (45%)
• Gaps: 60/284 - (21%)

  Fly   452 DALSVGDALHTLHGSSG----NGS-AGGAPTAHALHNNNNNTTNNNNHSLKAE-------GINGA 504
            ||...|..:|...|..|    :|| ..|.|....|             .:.||       |:|.|
Human    47 DAEPRGSEVHNAGGGGGDRKLDGSEPPGGPCEAVL-------------EMDAERMGEPQPGLNAA 98

  Fly   505 GS-GHDDSLNEDGIEEDIDDVDDADGSGGGDANGSDGLPNK---KRKRRVLFTKAQTYELERRFR 565
            .. |....:.|.|:           |:.|....|......|   :||.||||::||...|||||:
Human    99 SPLGGGTRVPERGV-----------GNSGDSVRGGRSEQPKARQRRKPRVLFSQAQVLALERRFK 152

  Fly   566 QQRYLSAPEREHLASLIRLTPTQVKIWFQNHRYKTKRAQNEKGYE--GHPGLLHGHATHPHHPSA 628
            |||||||||||||||.::||.|||||||||.|||.||.:.:|..|  |||
Human   153 QQRYLSAPEREHLASALQLTSTQVKIWFQNRRYKCKRQRQDKSLELAGHP--------------- 202

  Fly   629 LPSPRRVAVPVLVRNGKPCLGDSSKLGADCVSVSSATATAMQNAAAHHLVALNGAAAYQHAAAAA 693
             .:|||||||||||:||||||...  ||.......:.|.:..:....:..|..||......|.|.
Human   203 -LTPRRVAVPVLVRDGKPCLGPGP--GAPAFPSPYSAAVSPYSCYGGYSGAPYGAGYGTCYAGAP 264

  Fly   694 AGLHAHAHAHAHAHGHGHPHAHAQ 717
            :|...|....:...|||..:|..|
Human   265 SGPAPHTPLASAGFGHGGQNATPQ 288

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
vnd	NP_476786.2	Homeobox	548..601	CDD:278475	40/52 (77%)
NKX2-6	NP_001129743.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	22..135		24/111 (22%)
		HOX	132..188	CDD:197696	42/55 (76%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165143178
Domainoid	1	1.000	46	1.000	Domainoid score	I12127
eggNOG	1	0.900	-	-		E2759_KOG0842
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.740