DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment vnd and nkx3-3

DIOPT Version :9

Sequence 1:	NP_476786.2	Gene:	vnd / 31003	FlyBaseID:	FBgn0261930	Length:	723	Species:	Drosophila melanogaster
Sequence 2:	XP_002937227.1	Gene:	nkx3-3 / 100485176	XenbaseID:	XB-GENE-479908	Length:	241	Species:	Xenopus tropicalis

Alignment Length:	240	Identity:	81/240 - (33%)
Similarity:	106/240 - (44%)	Gaps:	58/240 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly   417 SPVTSEVSYTYIGSNCQTSPALSGDYKSYSRSADSDALSVGDALHTLHGSSGNGSAGGAPTAHAL 481
            ||:||......:...|:                ||:.           |:.||| ..|..|..|.
Frog     7 SPLTSFSIQDILARTCR----------------DSNG-----------GNEGNG-GNGDNTGKAK 43

  Fly   482 HNNNNNTTNNNNHSLKAEGINGAGSGHDDSLNEDGIEEDIDD-------VDDADGSG------GG 533
            ..:..::|  ..||..|||.|......:..|..:..:.|.|.       ..:|..:|      .|
Frog    44 RTDEKSST--PPHSPSAEGHNDWPQADNPPLTPEKEKTDTDSGTEDSTWEPEAASTGAYTDPSSG 106

  Fly   534 DANGSDGLPNKKRKRRVLFTKAQTYELERRFRQQRYLSAPEREHLASLIRLTPTQVKIWFQNHRY 598
            |..| |...:.|::.|..|:.||.|||||||..|||||.|||..||:.::||.|||||||||.||
Frog   107 DLLG-DSPKSSKKRSRAAFSHAQVYELERRFSLQRYLSGPERADLAAALKLTETQVKIWFQNRRY 170

  Fly   599 KTKRAQNEKGYEGHPGLLHGHATHPHHPSALPSPRRVAVPVLVRN 643
            ||||.           |:   ||.....|:|...|:|||.|||::
Frog   171 KTKRK-----------LI---ATQTAPKSSLAPARKVAVRVLVKD 201

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
vnd	NP_476786.2	Homeobox	548..601	CDD:278475	35/52 (67%)
nkx3-3	XP_002937227.1	Homeobox	120..174	CDD:365835	36/53 (68%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910