DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Appl and CG42827

DIOPT Version :9

Sequence 1:	NP_001245448.1	Gene:	Appl / 31002	FlyBaseID:	FBgn0000108	Length:	890	Species:	Drosophila melanogaster
Sequence 2:	NP_651142.3	Gene:	CG42827 / 42763	FlyBaseID:	FBgn0262009	Length:	116	Species:	Drosophila melanogaster

Alignment Length:	144	Identity:	31/144 - (21%)
Similarity:	45/144 - (31%)	Gaps:	71/144 - (49%)

- Green bases have known domain annotations that are detailed below.

  Fly    79 DYCKKAYPNRDITNI-----VESSHYQKIGGWCRQGALNAAKCKGSHRWIKPFRCLGPFQSDALL 138
            |..::.| .|:..||     ::||.|              .||||..:
  Fly    23 DSLQEQY-EREQYNIRKKICLQSSEY--------------GKCKGRRK----------------- 55

  Fly   139 VPEGCLFDHIHNASRCWPFVRWNQTGAAACQERGMQMRSFAMLLPCGISVF----SGVEFVCCPK 199
                 |:.:....|:|..|:..|      |...|              ::|    |.|||  |.|
  Fly    56 -----LWFYNPKKSKCQVFIYSN------CGGNG--------------NLFYTKESCVEF--CGK 93

  Fly   200 HFKTDEIHVKKTDL 213
            :   |...|:||.|
  Fly    94 Y---DWKKVRKTGL 104

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Appl	NP_001245448.1	A4_EXTRA	26..198	CDD:128326	24/127 (19%)
		APP_N	33..141	CDD:280358	12/66 (18%)
		APP_Cu_bd	143..198	CDD:289676	12/58 (21%)
		APP_E2	387..580	CDD:289677
		GBP_C	<629..682	CDD:303769
		APP_amyloid	834..887	CDD:287486
CG42827	NP_651142.3	KU	40..92	CDD:238057	19/109 (17%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4295
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.900