DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Appl and Acp24A4

DIOPT Version :9

Sequence 1:	NP_001245448.1	Gene:	Appl / 31002	FlyBaseID:	FBgn0000108	Length:	890	Species:	Drosophila melanogaster
Sequence 2:	NP_001036330.1	Gene:	Acp24A4 / 318936	FlyBaseID:	FBgn0051779	Length:	78	Species:	Drosophila melanogaster

Alignment Length:	55	Identity:	11/55 - (20%)
Similarity:	22/55 - (40%)	Gaps:	13/55 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   210 KTDLPVMPAAQINSANDELVMNDEDDSNDSNYSK---------DANEDDLDDEDD 255
            |.::..:|||    ||...:......|.|:.|:.         ..||:..:.:::
  Fly    21 KNEICGLPAA----ANGNCLALFSRWSYDAQYNVCFNFIYGGCQGNENSFESQEE 71

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Appl	NP_001245448.1	A4_EXTRA	26..198	CDD:128326
		APP_N	33..141	CDD:280358
		APP_Cu_bd	143..198	CDD:289676
		APP_E2	387..580	CDD:289677
		GBP_C	<629..682	CDD:303769
		APP_amyloid	834..887	CDD:287486
Acp24A4	NP_001036330.1	Kunitz_BPTI	24..77	CDD:278443	10/52 (19%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4295
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.900