DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment Appl and Hhip

DIOPT Version :9

Sequence 1:NP_001245448.1 Gene:Appl / 31002 FlyBaseID:FBgn0000108 Length:890 Species:Drosophila melanogaster
Sequence 2:NP_001178746.1 Gene:Hhip / 291936 RGDID:1564108 Length:700 Species:Rattus norvegicus


Alignment Length:63 Identity:17/63 - (26%)
Similarity:25/63 - (39%) Gaps:25/63 - (39%)


- Green bases have known domain annotations that are detailed below.


  Fly    89 DITNIVESSHYQKIG------GW----CRQGALNAAKCKGSHR----WIKPFRC------LGP 131
            ||:.:..:.:|...|      ||    ||     .|||:...|    .::|.:|      |||
  Rat   607 DISRLCRNGYYTPTGKCCCSPGWEGDFCR-----IAKCEPPCRHGGVCVRPNKCLCKKGYLGP 664

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
ApplNP_001245448.1 A4_EXTRA 26..198 CDD:128326 17/63 (27%)
APP_N 33..141 CDD:280358 17/63 (27%)
APP_Cu_bd 143..198 CDD:289676
APP_E2 387..580 CDD:289677
GBP_C <629..682 CDD:303769
APP_amyloid 834..887 CDD:287486
HhipNP_001178746.1 Folate_rec 38..220 CDD:281076
GSDH 226..>428 CDD:285269
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG4295
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

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