DRSC/TRiP Functional Genomics Resources

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Protein Alignment Appl and C34F6.1

DIOPT Version :9

Sequence 1:NP_001245448.1 Gene:Appl / 31002 FlyBaseID:FBgn0000108 Length:890 Species:Drosophila melanogaster
Sequence 2:NP_509868.1 Gene:C34F6.1 / 181306 WormBaseID:WBGene00007938 Length:1043 Species:Caenorhabditis elegans


Alignment Length:237 Identity:52/237 - (21%)
Similarity:74/237 - (31%) Gaps:71/237 - (29%)


- Green bases have known domain annotations that are detailed below.


  Fly    50 YLSEEGRWVTDLSKKTTGPTCLRDKMDLLDYCKKAYPNRDIT------------NIVESSHYQKI 102
            |...:|.....|:|::...:|..     ::.|....|..|.|            |....:.|..:
 Worm   803 YKGMKGNSNNFLTKQSCRQSCKE-----MNPCGYGDPLVDTTGERMLCTGGQRVNSCPQNSYCHV 862

  Fly   103 GGWCRQGALNAAKCKGSHRWIKPFRCLGPFQSDALLVPEGC--------LFDHIHNASRCWPF-- 157
            |    ..||....|        |.|.:.|...   .|.||.        .||...|  ||.||  
 Worm   863 G----SSALTTLCC--------PKRKIDPCDQ---AVEEGTGSEDLPRWFFDRKQN--RCAPFTY 910

  Fly   158 --VRWNQ-------TGAAACQE------RGMQMRSFAMLLPCGISVFSGVEFVCCPKHFKTD-EI 206
              |..|:       |...||.|      .|:.:...:.:..|||.......|:|   |..:: .:
 Worm   911 GGVAGNENNFISQNTCMEACPEYRNYCPHGIPLIEGSTVTSCGIDKGCPEGFIC---HMSSEFNV 972

  Fly   207 HVKKTDLPVMPAAQINSANDELVMNDEDDSNDSNYSKDANED 248
            .:...|    |.....||.|....|    :.:..|..|||.|
 Worm   973 SICCQD----PMDFCLSARDSGPCN----NFEKRYGYDANTD 1006

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
ApplNP_001245448.1 A4_EXTRA 26..198 CDD:128326 40/184 (22%)
APP_N 33..141 CDD:280358 19/102 (19%)
APP_Cu_bd 143..198 CDD:289676 19/79 (24%)
APP_E2 387..580 CDD:289677
GBP_C <629..682 CDD:303769
APP_amyloid 834..887 CDD:287486
C34F6.1NP_509868.1 Lustrin_cystein 186..231 CDD:291299
Kunitz_BPTI 238..289 CDD:278443
Lustrin_cystein 301..343 CDD:291299
Kunitz_BPTI 351..403 CDD:278443
Kunitz_BPTI 456..512 CDD:278443
KU 564..617 CDD:238057
Lustrin_cystein 623..663 CDD:291299
KU 667..720 CDD:238057
Lustrin_cystein 726..767 CDD:291299
Kunitz_BPTI 772..824 CDD:278443 4/20 (20%)
Lustrin_cystein 829..873 CDD:291299 10/55 (18%)
KU 878..931 CDD:238057 15/57 (26%)
Lustrin_cystein 937..977 CDD:291299 7/42 (17%)
Kunitz_BPTI 982..1033 CDD:278443 9/29 (31%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG4295
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

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