DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment Appl and R12A1.3

DIOPT Version :9

Sequence 1:NP_001245448.1 Gene:Appl / 31002 FlyBaseID:FBgn0000108 Length:890 Species:Drosophila melanogaster
Sequence 2:NP_503410.3 Gene:R12A1.3 / 178632 WormBaseID:WBGene00020017 Length:271 Species:Caenorhabditis elegans


Alignment Length:165 Identity:40/165 - (24%)
Similarity:56/165 - (33%) Gaps:48/165 - (29%)


- Green bases have known domain annotations that are detailed below.


  Fly   183 PCGISVFSGVEFVC-----CPKHFK----------------TDEIHVKKTDLPVMPAAQINSAND 226
            |.|||||......|     ||...|                .|.:.:..|.:..:|.| :.|...
 Worm   110 PLGISVFQDNTIGCWMDSNCPGIQKCCVEPNPVTNSATRICRDPVGIASTSICSLPLA-VGSCTA 173

  Fly   227 ELVMNDEDDS----NDSNYSK-DANEDDLDDEDDLMGDDEEDDMVADEAATAGGSPNTGS---SG 283
            ..|....|.|    |...||. ..|.::........|             |.|.|..||:   ..
 Worm   174 PAVRFYYDASSGRCNQFMYSGCGGNANNFQSLSSCQG-------------TCGQSGVTGTPACPA 225

  Fly   284 DSNSGSLDDINAEYDSGEEGDNYEEDGAGSESEAE 318
            |:||| |:.:.|..|:    .|.::|..|.|:.|:
 Worm   226 DANSG-LNCLFAHADA----CNSDKDCLGRENTAQ 255

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
ApplNP_001245448.1 A4_EXTRA 26..198 CDD:128326 7/19 (37%)
APP_N 33..141 CDD:280358
APP_Cu_bd 143..198 CDD:289676 7/19 (37%)
APP_E2 387..580 CDD:289677
GBP_C <629..682 CDD:303769
APP_amyloid 834..887 CDD:287486
R12A1.3NP_503410.3 Kunitz_BPTI 161..212 CDD:333766 11/64 (17%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG4295
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

Return to query results.
Submit another query.