DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4293 and PDIL5-4

DIOPT Version :9

Sequence 1:	NP_001033816.1	Gene:	CG4293 / 31001	FlyBaseID:	FBgn0024983	Length:	441	Species:	Drosophila melanogaster
Sequence 2:	NP_680742.2	Gene:	PDIL5-4 / 828816	AraportID:	AT4G27080	Length:	532	Species:	Arabidopsis thaliana

Alignment Length:	484	Identity:	91/484 - (18%)
Similarity:	165/484 - (34%)	Gaps:	171/484 - (35%)

- Green bases have known domain annotations that are detailed below.

  Fly    23 AFKKVPEKYTETSEIGGTLSLLSRLLIVYLVYTELHYYWHETDIVYQFEPDIALDEQVQ---MHV 84
            |.||:|...||.|..|..||:::.|.:::|...||:.|     :.......:.:|....   :.:
plant    64 ASKKIPRDLTEASLSGAGLSIIAALSMIFLFGMELNNY-----LAVSTSTSVIVDRSADGDFLRL 123

  Fly    85 DITVAMPCAS--------------------------------------------LSGVDLMDETQ 105
            |..::.|..|                                            ||.::..|||.
plant   124 DFNISFPSLSCEFASVDVSDVLGTNRLNVTKTIRKFSIDSNMRPTGSEFHAGEVLSLINHGDETG 188

  Fly   106 QDVFA---------YGTLQRE---------GVW----------WEMSEHDRLQFQAIQIQNHYLR 142
            :::..         :.|...:         ..|          ||.:        |.||:..|..
plant   189 EEIVEDSVPLTGRNFDTFTHQFPILVVNFYAPWCYWCNLLKPSWEKA--------AKQIKERYDP 245

  Fly   143 EEFHSVADVLFK-------DIMRDNH----PARESASKAPAAPPPGA------------------ 178
            |....|  :|.|       |:.|.||    |:.....|........|
plant   246 EMDGRV--ILAKVDCTQEGDLCRRNHIQGYPSIRIFRKGSDLKDDNAHHDHESYYGDRDTESLVK 308

  Fly   179 --LPLSVDLH-GRHNVQPESKFD-------------ACRLHGTLGINKVAGVLHLVGGAQPVVGL 227
              :.|...:| ..||:..|.|.|             .||:.|.:.:.||.|  :|:..|:.....
plant   309 MVVSLVEPIHLEPHNLALEDKSDNSSRTLKKAPSTGGCRVEGYMRVKKVPG--NLMVSARSGSHS 371

  Fly   228 FEDHWMIELRRMPANFTHRINRLSFGQ---------------YSGRIVQPLEGDEIVIHEEA--- 274
            |:...|        |.:|.:|.||||:               |.|.....|:|...:...:.
plant   372 FDSSQM--------NMSHVVNHLSFGRRIMPQKFSEFKRLSPYLGLSHDRLDGRSFINQRDLGPN 428

  Fly   275 TTVQYFLKVVPTEIHQT--FTTIYAFQYAVTENVRKLDSERNSYGSPGIYFKYDWSALKIIVRND 337
            .|::::|::|.||:.::  ...:.|::|....:|      .:||..|...|.::.|.:::::..:
plant   429 VTIEHYLQIVKTEVVKSNGQALVEAYEYTAHSSV------AHSYYLPVAKFHFELSPMQVLITEN 487

  Fly   338 RDHLVTFAIRLCSIISGIIVISGAINALL 366
            ......|...:|:||.|:..::|.::::|
plant   488 SKSFSHFITNVCAIIGGVFTVAGILDSIL 516

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4293	NP_001033816.1	ERGIC_N	19..104	CDD:290561	22/127 (17%)
CG4293	NP_001033816.1	COPIIcoated_ERV	<200..349	CDD:285244	35/168 (21%)
PDIL5-4	NP_680742.2	ERGIC_N	67..150	CDD:290561	17/87 (20%)
		PDI_a_family	196..308	CDD:239259	19/121 (16%)
		COPIIcoated_ERV	<345..513	CDD:285244	40/183 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0445
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1318747at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10984
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.920