DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4293 and PDIL5-3

DIOPT Version :9

Sequence 1:	NP_001033816.1	Gene:	CG4293 / 31001	FlyBaseID:	FBgn0024983	Length:	441	Species:	Drosophila melanogaster
Sequence 2:	NP_566664.1	Gene:	PDIL5-3 / 821603	AraportID:	AT3G20560	Length:	483	Species:	Arabidopsis thaliana

Alignment Length:	479	Identity:	90/479 - (18%)
Similarity:	164/479 - (34%)	Gaps:	152/479 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly    19 KNLDAFKKVPEKYTETSEIGGTLSLLSRLLIVYLVYTELHYYWHETDIVYQFEPDIALDEQVQMH 83
            |::|.::|:|...||.|..|..||:::.|.:::|...||..|. |.:.......|.:.|... :.
plant     8 KSVDFYRKIPRDLTEASLSGAGLSIVAALFMMFLFGMELSSYL-EVNTTTAVIVDKSSDGDF-LR 70

  Fly    84 VDITVAMPCAS--LSGVDLMD------------------------------------------ET 104
            :|..::.|..|  .:.||:.|                                          ||
plant    71 IDFNISFPALSCEFASVDVSDVLGTNRLNITKTVRKFPIDPHLRSTGAEFHSGLALHNINHGEET 135

  Fly   105 QQDVFAYGTLQREGVWWEMSEH-----------------DRLQFQAIQIQNHYLREEFHSVAD-- 150
            ::: |..|.:......:|...|                 :||:....:..| .:::.:...||
plant   136 KEE-FPDGAIPLTSASFEALSHHFPILVVNFNAPWCYWSNRLKPSWEKAAN-IIKQRYDPEADGR 198

  Fly   151 VLFKDIMRDNHPARESASKAPAAPPPGALPLSVDL---HGRHN---------------------- 190
            ||..::.....||....:.....|.........||   ||.|.
plant   199 VLLGNVDCTEEPALCKRNHIQGYPSIRIFRKGSDLREDHGHHEHESYYGDRDTDSIVKMVEGLVA 263

  Fly   191 -VQPESKFDA--------------------CRLHGTLGINKVAGVLHLVGGAQPVVGLFEDHWMI 234
             :.||:...|                    ||:.|.:.:.||.|  :||..|......|:...|
plant   264 PIHPETHKVALDGKSNDTVKHLKKGPVTGGCRVEGYVRVKKVPG--NLVISAHSGAHSFDSSQM- 325

  Fly   235 ELRRMPANFTHRINRLSFGQ---------------YSGRIVQPLEGDEIVIHEE---ATTVQYFL 281
                   |.:|.::..|||:               |.|.....|:|...:...|   ..|::::|
plant   326 -------NMSHVVSHFSFGRMISPRLLTDMKRLLPYLGLSHDRLDGKAFINQHEFGANVTIEHYL 383

  Fly   282 KVVPTEI-----HQTFTTIYAFQYAVTENVRKLDSERNSYGSPGIYFKYDWSALKIIVRNDRDHL 341
            :.|.||:     .|..:.|..::|....:|.:      :|..|...|.::.|.::|::..:....
plant   384 QTVKTEVITRRSGQEHSLIEEYEYTAHSSVAQ------TYYLPVAKFHFELSPMQILITENPKSF 442

  Fly   342 VTFAIRLCSIISGIIVISGAINAL 365
            ..|...||:||.|:..::|.::::
plant   443 SHFITNLCAIIGGVFTVAGILDSI 466

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4293	NP_001033816.1	ERGIC_N	19..104	CDD:290561	24/128 (19%)
CG4293	NP_001033816.1	COPIIcoated_ERV	<200..349	CDD:285244	36/171 (21%)
PDIL5-3	NP_566664.1	ERGIC_N	7..98	CDD:372756	24/91 (26%)
		PDI_a_family	144..256	CDD:239259	17/112 (15%)
		COPIIcoated_ERV	<293..464	CDD:369627	42/186 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0445
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1318747at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10984
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.920