Protein Alignment CG4293 and ERGIC3

DIOPT Version :9

• Sequence 1: NP_001033816.1
• Gene: CG4293 / 31001
• FlyBaseID: FBgn0024983
• Length: 441
• Species: Drosophila melanogaster
• Sequence 2: NP_938408.1
• Gene: ERGIC3 / 51614
• HGNCID: 15927
• Length: 388
• Species: Homo sapiens
• Alignment Length: 402
• Identity: 103/402 - (25%)
• Similarity: 172/402 - (42%)
• Gaps: 92/402 - (22%)

  Fly    19 KNLDAFKKVPEKYTETSEIGGTLSLLSRLLIVYLVYTELHYYWHETDIVYQFEPDIALD----EQ 79
            |..||:.|..|.:...:..|.|::::|.||::.|..:||.||     :..:..|::.:|    ::
Human     8 KQFDAYPKTLEDFRVKTCGGATVTIVSGLLMLLLFLSELQYY-----LTTEVHPELYVDKSRGDK 67

  Fly    80 VQMHVDITVA-MPCASLSGVDLMD---ETQQDVFAYGTLQREGVWWEMSEHD----RLQFQAIQI 136
            :::::|:... ||||.|| :|.||   |.|.||                ||:    ||....|.:
Human    68 LKINIDVLFPHMPCAYLS-IDAMDVAGEQQLDV----------------EHNLFKQRLDKDGIPV 115

  Fly   137 QNHYLREEFHSVADVLF------------------KDI--------MRDNHPARESASKAPAAPP 175
            .:...|.|...|...:|                  :||        :|:.:..|..|.|.|.
Human   116 SSEAERHELGKVEVTVFDPDSLDPDRCESCYGAEAEDIKCCNTCEDVREAYRRRGWAFKNPD--- 177

  Fly   176 PGALPLSVD---LHGRHNVQPESKFDACRLHGTLGINKVAGVLHLVGG-----AQPVVGLFEDHW 232
                  :::   ..|......|.|.:.|:::|.|.:|||||..|...|     :...|...|.|.
Human   178 ------TIEQCRREGFSQKMQEQKNEGCQVYGFLEVNKVAGNFHFAPGKSFQQSHVHVHAVEIHD 236

  Fly   233 MIELRRMPANFTHRINRLSFGQ-YSGRIVQPLEGDEIVIHEEATTVQYFLKVVPT-------EIH 289
            :........|.||.|..||||: |.| ||.||:...:...:.:...|||:|||||       |:.
Human   237 LQSFGLDNINMTHYIQHLSFGEDYPG-IVNPLDHTNVTAPQASMMFQYFVKVVPTVYMKVDGEVL 300

  Fly   290 QTFTTIYAFQYAVTENVRKLDSERNSYGSPGIYFKYDWSALKIIVRNDRDHLVTFAIRLCSIISG 354
            :|      .|::||.:.:..:......|.||::..|:.|.:.:.:.........|...:|:||.|
Human   301 RT------NQFSVTRHEKVANGLLGDQGLPGVFVLYELSPMMVKLTEKHRSFTHFLTGVCAIIGG 359

  Fly   355 IIVISGAINALL 366
            :..::|.|::|:
Human   360 MFTVAGLIDSLI 371

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4293	NP_001033816.1	ERGIC_N	19..104	CDD:290561	27/92 (29%)
		COPIIcoated_ERV	<200..349	CDD:285244	46/161 (29%)
ERGIC3	NP_938408.1	ERGIC_N	7..97	CDD:404692	28/94 (30%)
		COPIIcoated_ERV	145..368	CDD:400361	61/238 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0445
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1318747at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.820