DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment elav and fne

DIOPT Version :9

Sequence 1:NP_001245447.1 Gene:elav / 31000 FlyBaseID:FBgn0260400 Length:483 Species:Drosophila melanogaster
Sequence 2:NP_001096965.1 Gene:fne / 32245 FlyBaseID:FBgn0086675 Length:356 Species:Drosophila melanogaster


Alignment Length:366 Identity:222/366 - (60%)
Similarity:272/366 - (74%) Gaps:33/366 - (9%)


- Green bases have known domain annotations that are detailed below.


  Fly   130 NGNAGSGSQNGSNGSTETRTNLIVNYLPQTMTEDEIRSLFSSVGEIESVKLIRDKSQ------VY 188
            ||:| :||.:|||  .|:||||||||||||||::|:||||||:||:||.||:|||..      ..
  Fly    10 NGSA-NGSVDGSN--DESRTNLIVNYLPQTMTQEEMRSLFSSIGELESCKLVRDKVSGNLVLPAS 71

  Fly   189 IDPLNPQAPSKGQSLGYGFVNYVRPQDAEQAVNVLNGLRLQNKTIKVSFARPSSDAIKGANLYVS 253
            :..||| |..:|||||||||||||.:|||:|||.|||||||||.||||:|||||::|||||||||
  Fly    72 LTALNP-ALQQGQSLGYGFVNYVRAEDAEKAVNTLNGLRLQNKVIKVSYARPSSESIKGANLYVS 135

  Fly   254 GLPKTMTQQELEAIFAPFGAIITSRIL-QNAGNDTQTKGVGFIRFDKREEATRAIIALNGTTPSS 317
            ||||.::|.:||.:||.||.||||||| .|...  .:|||||||||:|.||.|||..|||.||..
  Fly   136 GLPKNLSQPDLEGMFASFGKIITSRILCDNISG--LSKGVGFIRFDQRNEAERAIQELNGKTPKG 198

  Fly   318 CTDPIVVKFSNTPGSTSKI-IQPQLPAFLNPQ---LVRRIGGAMHTPVNKGLARFSPMAGDML-D 377
            ..:||.|||:|.|.:::|. |.|.|.|:|.||   ..||:.||:   .:.|..|:||:|||:| :
  Fly   199 YAEPITVKFANNPSNSAKAQIAPPLTAYLTPQAAAATRRLAGAL---PSAGRIRYSPLAGDLLAN 260

  Fly   378 VMLPNGLGAAAAAATTLASGPGGAYPIFIYNLAPETEEAALWQLFGPFGAVQSVKIVKDPTTNQC 442
            .:||..       |.|     |..:.||:|||||||||..|||||||||||||||:::|..|::|
  Fly   261 SILPGN-------AMT-----GSGWCIFVYNLAPETEENVLWQLFGPFGAVQSVKVIRDLQTSKC 313

  Fly   443 KGYGFVSMTNYDEAAMAIRALNGYTMGNRVLQVSFKTNKAK 483
            ||:|||:|||||||.:||::|||||:|||||||||||||.|
  Fly   314 KGFGFVTMTNYDEAVVAIQSLNGYTLGNRVLQVSFKTNKTK 354

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
elavNP_001245447.1 ELAV_HUD_SF 146..483 CDD:273741 213/348 (61%)
fneNP_001096965.1 ELAV_HUD_SF 23..354 CDD:273741 213/348 (61%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 1 1.000 81 1.000 Domainoid score I5464
eggNOG 1 0.900 - - E1_KOG0145
Homologene 00.000 Not matched by this tool.
Inparanoid 1 1.050 253 1.000 Inparanoid score I1971
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D425303at33208
OrthoFinder 1 1.000 - - FOG0000313
OrthoInspector 1 1.000 - - mtm1072
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - P PTHR10352
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 1 1.000 - - X326
98.970

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