DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment elav and elavl4

DIOPT Version :9

Sequence 1:	NP_001245447.1	Gene:	elav / 31000	FlyBaseID:	FBgn0260400	Length:	483	Species:	Drosophila melanogaster
Sequence 2:	NP_001231529.1	Gene:	elavl4 / 30737	ZFINID:	ZDB-GENE-990415-246	Length:	411	Species:	Danio rerio

Alignment Length:	424	Identity:	201/424 - (47%)
Similarity:	267/424 - (62%)	Gaps:	59/424 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    90 AVVAQQAVVQQQQQQAAAVVQQAAVQQAVVPQPQ----QAQPNTNGNAGSGSQNGSNGST----- 145
            |:::.:...:.|.:||.....|...::.::.||:    ..:|.......|.:.||.:.::
Zfish    11 ALLSNEGSTETQWRQADLPQLQGWAEKGLLTQPKMIISNMEPQVTNGPNSATANGPSSNSRSCPS 75

  Fly   146 ---------ETRTNLIVNYLPQTMTEDEIRSLFSSVGEIESVKLIRDKSQVYIDPLNPQAPSKGQ 201
                     :::||||||||||.||::|.||||.|:|||||.||:|||             ..||
Zfish    76 PMQTGGSNDDSKTNLIVNYLPQNMTQEEFRSLFGSIGEIESCKLVRDK-------------ITGQ 127

  Fly   202 SLGYGFVNYVRPQDAEQAVNVLNGLRLQNKTIKVSFARPSSDAIKGANLYVSGLPKTMTQQELEA 266
            |||||||||:.|:|||:|:|.|||||||.||||||:|||||.:|:.||||||||||||||:|||.
Zfish   128 SLGYGFVNYIDPKDAEKAINTLNGLRLQTKTIKVSYARPSSASIRDANLYVSGLPKTMTQKELEQ 192

  Fly   267 IFAPFGAIITSRIL--QNAGNDTQTKGVGFIRFDKREEATRAIIALNGTTPSSCTDPIVVKFSNT 329
            :|:.:|.|||||||  |..|....::||||||||||.||..||..|||..||...:||.|||:|.
Zfish   193 LFSQYGRIITSRILVDQVTGPTGGSRGVGFIRFDKRIEAEEAIKGLNGQKPSGAAEPITVKFANN 257

  Fly   330 PG-STSKIIQPQLPAFLNPQLVRRIGGAMHTPVNK-----------GLARFSPMAGDMLDVMLPN 382
            |. .||:.:..||  :.:|.  ||..|.:|....:           |:.||||:..|.:
Zfish   258 PSQKTSQALLSQL--YQSPN--RRYPGPLHHQAQRFRLDNLLNMAYGVKRFSPITIDSM------ 312

  Fly   383 GLGAAAAAATTLASGPGGAYPIFIYNLAPETEEAALWQLFGPFGAVQSVKIVKDPTTNQCKGYGF 447
                .:.....:....|..:.||:|||:|:::|:.|||||||||||.:||:::|..||:|||:||
Zfish   313 ----TSLVGMNIPGHTGTGWCIFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGF 373

  Fly   448 VSMTNYDEAAMAIRALNGYTMGNRVLQVSFKTNK 481
            |:|||||||||||.:||||.:|:|||||||||||
Zfish   374 VTMTNYDEAAMAIASLNGYRLGDRVLQVSFKTNK 407

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
elav	NP_001245447.1	ELAV_HUD_SF	146..483	CDD:273741	190/350 (54%)
elavl4	NP_001231529.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	50..89		4/38 (11%)
elavl4	NP_001231529.1	ELAV_HUD_SF	85..410	CDD:273741	190/350 (54%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0145
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG55893
OrthoDB	1	1.010	-	-		D425303at33208
OrthoFinder	1	1.000	-	-		FOG0000313
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10352
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X326
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	10	9.890