Protein Alignment elav and ELAVL3

DIOPT Version :9

• Sequence 1: NP_001245447.1
• Gene: elav / 31000
• FlyBaseID: FBgn0260400
• Length: 483
• Species: Drosophila melanogaster
• Sequence 2: XP_024307178.1
• Gene: ELAVL3 / 1995
• HGNCID: 3314
• Length: 424
• Species: Homo sapiens
• Alignment Length: 432
• Identity: 199/432 - (46%)
• Similarity: 251/432 - (58%)
• Gaps: 108/432 - (25%)

  Fly   131 GNAGSGSQN----GSNGST-ETRTNLIVNYLPQTMTEDEIRSLFSSVGEIESVKLIRDKSQVYID 190
            |.||....|    |:||:| :::||||||||||.||:||.:|||.|:|:|||.||:|||
Human    16 GPAGPALPNGPLLGTNGATDDSKTNLIVNYLPQNMTQDEFKSLFGSIGDIESCKLVRDK------ 74

  Fly   191 PLNPQAPSKGQSLGYGFVNYVRPQDAEQAVNVLNGLRLQNKTIKVSFARPSSDAIKGANLYVSGL 255
                   ..|||||||||||..|.||::|:|.||||:||.||||||:|||||.:|:.||||||||
Human    75 -------ITGQSLGYGFVNYSDPNDADKAINTLNGLKLQTKTIKVSYARPSSASIRDANLYVSGL 132

  Fly   256 PKTMTQQELEAIFAPFGAIITSRIL-------------------------QNAGNDTQ------- 288
            ||||:|:|:|.:|:.:|.|||||||                         .|.|..|:
Human   133 PKTMSQKEMEQLFSQYGRIITSRILVDQVTGQAVREGAPGGGAGQRQSGGTNVGKPTKMPGHEAG 197

  Fly   289 ------------------------TKGVGFIRFDKREEATRAIIALNGTTPSSCTDPIVVKFSNT 329
                                    ::||||||||||.||..||..|||..|....:||.|||:|.
Human   198 KGEVGLHRRGQGRRDGHPCPLAGVSRGVGFIRFDKRIEAEEAIKGLNGQKPLGAAEPITVKFANN 262

  Fly   330 PGSTSKIIQPQLPAFLNPQLVRRIGGAMH-------------------TPVNKGLARFSPMAGDM 375
            |   |:.....|...|.....||..|.:|                   :|::. :|||||:|.|
Human   263 P---SQKTGQALLTHLYQSSARRYAGPLHHQTQRFRLDNLLNMAYGVKSPLSL-IARFSPIAID- 322

  Fly   376 LDVMLPNGLGAAAAAATTLASGPGGA-YPIFIYNLAPETEEAALWQLFGPFGAVQSVKIVKDPTT 439
                     |.:..|...|:.|..|| :.||:|||:||.:|:.|||||||||||.:||:::|.||
Human   323 ---------GMSGLAGVGLSGGAAGAGWCIFVYNLSPEADESVLWQLFGPFGAVTNVKVIRDFTT 378

  Fly   440 NQCKGYGFVSMTNYDEAAMAIRALNGYTMGNRVLQVSFKTNK 481
            |:|||:|||:|||||||||||.:||||.:|.|||||||||:|
Human   379 NKCKGFGFVTMTNYDEAAMAIASLNGYRLGERVLQVSFKTSK 420

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
elav	NP_001245447.1	ELAV_HUD_SF	146..483	CDD:273741	191/412 (46%)
ELAVL3	XP_024307178.1	RRM	36..423	CDD:330708	191/412 (46%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0145
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG55893
OrthoDB	1	1.010	-	-		D425303at33208
OrthoFinder	1	1.000	-	-		FOG0000313
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10352
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X326
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	9	8.890