Protein Alignment elav and ELAVL1

DIOPT Version :10

• Sequence 1: NP_525033.1
• Gene: elav / 31000
• FlyBaseID: FBgn0260400
• Length: 483
• Species: Drosophila melanogaster
• Sequence 2: XP_047294339.1
• Gene: ELAVL1 / 1994
• HGNCID: 3312
• Length: 353
• Species: Homo sapiens
• Alignment Length: 341
• Identity: 183/341 - (53%)
• Similarity: 234/341 - (68%)
• Gaps: 41/341 - (12%)

  Fly   148 RTNLIVNYLPQTMTEDEIRSLFSSVGEIESVKLIRDKSQVYIDPLNPQAPSKGQSLGYGFVNYVR 212
            |||||||||||.||:||:||||||:||:||.||||||             ..|.||||||||||.
Human    46 RTNLIVNYLPQNMTQDELRSLFSSIGEVESAKLIRDK-------------VAGHSLGYGFVNYVT 97

  Fly   213 PQDAEQAVNVLNGLRLQNKTIKVSFARPSSDAIKGANLYVSGLPKTMTQQELEAIFAPFGAIITS 277
            .:|||:|:|.|||||||:||||||:|||||:.||.||||:||||:||||:::|.:|:.||.||.|
Human    98 AKDAERAINTLNGLRLQSKTIKVSYARPSSEVIKDANLYISGLPRTMTQKDVEDMFSRFGRIINS 162

  Fly   278 RIL--QNAGNDTQTKGVGFIRFDKREEATRAIIALNGTTPSSCTDPIVVKFSNTPGSTSKI-IQP 339
            |:|  |..|   .::||.|||||||.||..||.:.||..|...::||.|||:..|.....: :..
Human   163 RVLVDQTTG---LSRGVAFIRFDKRSEAEEAITSFNGHKPPGSSEPITVKFAANPNQNKNVALLS 224

  Fly   340 QLPAFLNPQLVRRIGGAMHTPVNKGLARFSPMAGDMLDVMLPNGLGAAAAAATTLASGPGGA--- 401
            ||  :.:|  .||.||.:|....:  .|||||..|.:     :||..        .:.||.|
Human   225 QL--YHSP--ARRFGGPVHHQAQR--FRFSPMGVDHM-----SGLSG--------VNVPGNASSG 270

  Fly   402 YPIFIYNLAPETEEAALWQLFGPFGAVQSVKIVKDPTTNQCKGYGFVSMTNYDEAAMAIRALNGY 466
            :.||||||..:.:|..|||:|||||||.:||:::|..||:|||:|||:||||:||||||.:||||
Human   271 WCIFIYNLGQDADEGILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTNYEEAAMAIASLNGY 335

  Fly   467 TMGNRVLQVSFKTNKA 482
            .:|:::|||||||||:
Human   336 RLGDKILQVSFKTNKS 351

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
elav	NP_525033.1	ELAV_HUD_SF	146..483	CDD:273741	183/341 (54%)
ELAVL1	XP_047294339.1	ELAV_HUD_SF	46..353	CDD:273741	183/341 (54%)