DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment svr and Cpm

DIOPT Version :9

Sequence 1:NP_001284744.1 Gene:svr / 30998 FlyBaseID:FBgn0004648 Length:1439 Species:Drosophila melanogaster
Sequence 2:NP_081744.1 Gene:Cpm / 70574 MGIID:1917824 Length:443 Species:Mus musculus


Alignment Length:387 Identity:167/387 - (43%)
Similarity:243/387 - (62%) Gaps:24/387 - (6%)


- Green bases have known domain annotations that are detailed below.


  Fly    40 YASQEQLEDLFAGLEKAYPNQAKVHFLGRSLEGRNLLALQISRNTRSRNLLTPPVKYIANMHGDE 104
            |..||.:|.....:.:.|.:...:|.:|:|:.||||..|.:.:..:...:..|..||:|||||||
Mouse    22 YHHQEGMEAFLKSVAQNYSSITHLHSIGKSVRGRNLWVLVVGQTPKEHRVGIPEFKYVANMHGDE 86

  Fly   105 TVGRQLLVYMAQYLLGNHERISDLGQLVNSTDIYLVPTMNPDGYALSQEGNCESLPNYV--GRGN 167
            ||||:||:::..||:.::.:..::..|::||.|:::|:|||||:...|:.:|     |.  ||.|
Mouse    87 TVGRELLLHLIDYLVSSYRKDPEITHLIDSTRIHIMPSMNPDGFEAVQKPDC-----YYSNGREN 146

  Fly   168 AANIDLNRDFPDRLEQSHVHQLRAQSRQPETAALVNWIVSKPFVLSANFHGGAVVASYPYDNSL- 231
            ..|.||||:|||..|.::|      ::||||.|::.|:.::.||||||.||||:|||||:||.: 
Mouse   147 YNNYDLNRNFPDAFENNNV------TKQPETLAIMEWLKTETFVLSANLHGGALVASYPFDNGVQ 205

  Fly   232 AHNECCEESLTPDDRVFKQLAHTYSDNHPIMRKGNNCND--SFSGGITNGAHWYELSGGMQDFNY 294
            |.......||||||.||:.||:||:..:|.|.||:.|.:  :|..||.||..||.|.|||||:||
Mouse   206 ATGTLLSRSLTPDDDVFQHLAYTYASRNPNMTKGDQCKNKRNFPNGIINGYSWYPLQGGMQDYNY 270

  Fly   295 AFSNCFELTIELSCCKYPAASTLPQEWQRNKASLLQLLRQAHIGIKGLVTDASGFPIADANVYVA 359
            .::.|||:|:||||||||....||..|..|||||::.::|.|:|:||.|.|.||.|:  .||.|.
Mouse   271 IWAQCFEITLELSCCKYPREEKLPLFWNDNKASLIEYIKQVHLGVKGQVFDQSGAPL--PNVIVE 333

  Fly   360 GLEEK---PMRTSKRGEYWRLLTPGLYSVHASAFGYQTSAPQQVRVTNDNQ--EALRLDFKL 416
            ..:.|   |.||:|.|||:.||.||.|.::.:..|:. |...::.:...:|  .||:.||.|
Mouse   334 VQDRKHICPFRTNKLGEYYLLLLPGSYVINVTVPGHD-SYLTKLTIPGKSQPFSALKKDFHL 394

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
svrNP_001284744.1 M14_CPD_I 40..334 CDD:199850 133/298 (45%)
Peptidase_M14NE-CP-C_like 338..416 CDD:200604 31/82 (38%)
M14_CP_N-E_like 456..759 CDD:199842
Peptidase_M14NE-CP-C_like 763..839 CDD:200604
CarbopepD_reg_2 1125..1202 CDD:290434
CarboxypepD_reg 1223..1301 CDD:290350
CpmNP_081744.1 M14_CPM 22..310 CDD:349438 133/298 (45%)
Peptidase_M14NE-CP-C_like 314..394 CDD:200604 31/82 (38%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG2649
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 1 0.950 - 0 Normalized mean entropy S4288
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D101221at2759
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 1 1.030 - avgDist Average_Evolutionary_Distance R3496
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
54.800

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