DRSC/TRiP Functional Genomics Resources

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Protein Alignment svr and Cpxm2

DIOPT Version :10

Sequence 1:NP_996319.1 Gene:svr / 30998 FlyBaseID:FBgn0004648 Length:1439 Species:Drosophila melanogaster
Sequence 2:NP_061355.3 Gene:Cpxm2 / 55987 MGIID:1926006 Length:764 Species:Mus musculus


Alignment Length:584 Identity:177/584 - (30%)
Similarity:260/584 - (44%) Gaps:149/584 - (25%)


- Green bases have known domain annotations that are detailed below.


  Fly   271 SFSGGITNGAH-WYELSGGMQDFNYAFSNCFELTIELSCCKYPAASTL----PQEWQRNKASLLQ 330
            |:...::|.:| |..:..|..|..:..::..|:.: |:....|..:..    ||.|..|.:..::
Mouse   232 SYKVMVSNDSHTWVTVKNGSGDMIFEGNSEKEIPV-LNELPVPMVARYIRINPQSWFDNGSICMR 295

  Fly   331 LLRQAHIGIKGLVTDASGFPIADANVYVAGLEEKPMRTSKRGEYWRLLTPGLYSVHASAFGYQTS 395
            :             :..|.|:.|.|.|                |.|                   
Mouse   296 M-------------EILGCPLPDPNNY----------------YHR------------------- 312

  Fly   396 APQQVRVTNDNQEALRLDFKLAPVETNFDGNFRKVKVERSEPPQKLKKQFNGFLTPTKYEHHNFT 460
             ..::..|:|      ||||                                        |||:.
Mouse   313 -RNEMTTTDD------LDFK----------------------------------------HHNYK 330

  Fly   461 AMESYLRAISSSYPSLTRLYSIGKSVQGRDLWVLEIFATPGSHVPGVPEFKYVANMHGNEVVGKE 525
            .|...::.::...|::||:|:||||.||..|:.:||...||.|..|.|||.|:|..|||||:|:|
Mouse   331 EMRQLMKVVNEMCPNITRIYNIGKSHQGLKLYAVEISDHPGEHEVGEPEFHYIAGAHGNEVLGRE 395

  Fly   526 LLLILTKYMLERY-GNDDRITKLVNGTRMHFLYSMNPDGYEISIE-GDRTGG--VGRANAHGIDL 586
            |||:|..::.:.| ..:.||.:||..||:|.|.|:||||||.:.| |...||  :||....|||:
Mouse   396 LLLLLLHFLCQEYSAQNARIVRLVEETRIHILPSLNPDGYEKAYEGGSELGGWSLGRWTHDGIDI 460

  Fly   587 NRNFP----------DQYGTDR---------------FNKVTEPEVAAVMNWTLSLPFVLSANLH 626
            |.|||          ||....|               .|.....|..||:.|...:||||..||.
Mouse   461 NNNFPDLNSLLWEAEDQQNAPRKVPNHYIAIPEWFLSENATVATETRAVIAWMEKIPFVLGGNLQ 525

  Fly   627 GGSLVANYPFDDNENDFNDPFMRLRNSSINGRKPNPTEDNALFKHLAGIYSNAHPTM--YLGQPC 689
            ||.||..||:|            :..|....::..||.|:.:|:.||..|::.|..|  ...:.|
Mouse   526 GGELVVAYPYD------------MVRSLWKTQEHTPTPDDHVFRWLAYSYASTHRLMTDARRRVC 578

  Fly   690 --ELFQNEFFPDGITNGAQWYSVTGGMQDWNYVRAGCLELTIEMGCDKFPKAAELSRYWEDHREP 752
              |.||.|   :|..|||.|::|.|.:.|::|:...|.||:|.:||||:|..:||...||::||.
Mouse   579 HTEDFQKE---EGTVNGASWHTVAGSLNDFSYLHTNCFELSIYVGCDKYPHESELPEEWENNRES 640

  Fly   753 LLQFIEQVHCGIHGFVHSTIGTPIAGAVVRLDGANHSTYSQVFGDYWKLALPGRHNLTVLGDNY 816
            |:.|:||||.||.|.|....|..|:.||:.::|.||...:...||||:|..||.:.:|...:.:
Mouse   641 LIVFMEQVHRGIKGIVRDLQGKGISNAVISVEGVNHDIRTASDGDYWRLLNPGEYVVTAKAEGF 704

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
svrNP_996319.1 M14_CPD_I 40..334 CDD:349440 13/67 (19%)
Peptidase_M14NE-CP-C_like 338..416 CDD:200604 12/77 (16%)
M14_CP_N-E_like 456..759 CDD:349431 128/335 (38%)
Peptidase_M14NE-CP-C_like 763..839 CDD:200604 19/54 (35%)
Peptidase_M14NE-CP-C_like 1124..1190 CDD:473874
CarboxypepD_reg 1223..1301 CDD:433354
Cpxm2NP_061355.3 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 71..136
FA58C 145..300 CDD:238014 13/81 (16%)
M14_CPX_like 326..647 CDD:349441 128/335 (38%)
Peptidase_M14NE-CP-C_like 651..726 CDD:200604 19/54 (35%)
Blue background indicates that the domain is not in the aligned region.

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