Protein Alignment svr and Cpxm1

DIOPT Version :10

• Sequence 1: NP_996319.1
• Gene: svr / 30998
• FlyBaseID: FBgn0004648
• Length: 1439
• Species: Drosophila melanogaster
• Sequence 2: NP_001099981.1
• Gene: Cpxm1 / 296156
• RGDID: 1306937
• Length: 722
• Species: Rattus norvegicus
• Alignment Length: 842
• Identity: 233/842 - (27%)
• Similarity: 349/842 - (41%)
• Gaps: 209/842 - (24%)

  Fly    88 NLLTPPVKYIANMHGDETVGRQLLVYMAQYLLGNHERISDLGQLVNSTDIYL-----VPTMNPDG 147
            ::..|..|  ||...::.| |..::...:.::...:::...|.||.:..:..     .||: |:
  Rat    40 SIAQPSTK--ANETSEQHV-RLRVIKKKKIVVKKRKKLRQPGPLVTARPLVTTHPAKTPTL-PE- 99

  Fly   148 YALSQEGNCESLPNYVGRGNAANIDLNRDFPDRLEQSHVHQLRAQSRQPETAALVNWIVSKPFVL 212
               .||..|..|                         .:..||....|.|.::      |:.|.|
  Rat   100 ---KQEPGCPPL-------------------------GLESLRVSDSQLEASS------SQSFGL 130

  Fly   213 SANFHGGAV-VASYPYDNSLAHNECCEESLTPDDRVFKQLAHTYSDNHPIMRKGNNCNDSFSGGI 276
            ..  |.|.: :.|...|..|.....|.|.               .||.|.::........|||.:
  Rat   131 GP--HRGRLNIQSGLEDGDLYDGAWCAEQ---------------QDNEPWLQVDARSPARFSGIV 178

  Fly   277 TNGAH--W-YELSGGMQDFNYAFSNCFELTIELSCCKYPAASTLPQEW--QRNKASLLQLLRQAH 336
            |.|.:  | |:   .:..|...|||.                  .|.|  .||.:.:..:
  Rat   179 TQGRNSVWRYD---WVTSFKVQFSND------------------SQSWWMSRNSSGMDMV----- 217

  Fly   337 IGIKGLVTDASGFPI-ADANVYVAGLEEKPMRTSKRGEYWRLLTPGLYSVHASAFGYQTSAPQQV 400
                        ||. :||...|..|..:|    :...:.||| |..:        :|..||
  Rat   218 ------------FPANSDAETPVLNLLPEP----QVARFIRLL-PQTW--------FQGGAP--- 254

  Fly   401 RVTNDNQEALRLDFKLAPVETNFDGNFRKVKVERSEPPQKLKKQFN-GFLTPTKYEHHNFTAMES 464
                    .||.:....||               |:|.....:... |......:.|||:.||..
  Rat   255 --------CLRAEILACPV---------------SDPNDLFPEAHTLGSSDSLDFRHHNYKAMRK 296

  Fly   465 YLRAISSSYPSLTRLYSIGKSVQGRDLWVLEIFATPGSHVPGVPEFKYVANMHGNEVVGKELLLI 529
            .::.::...|::||:||||||.||..|:|:|:...||.|..|.||.:|||.|||||.:|:||||:
  Rat   297 LMKEVNEQCPNITRIYSIGKSHQGLKLYVMEMSDHPGEHELGEPEVRYVAGMHGNEALGRELLLL 361

  Fly   530 LTKYMLERY-GNDDRITKLVNGTRMHFLYSMNPDGYEISI-EGDRTGG--VGRANAHGIDLNRNF 590
            |.:::...: ..|.|:|:|:..||:|.|.||||||||.:. :|....|  .||....|||||.||
  Rat   362 LMQFLCREFLRGDPRVTRLLTETRIHLLPSMNPDGYETAYHKGSELVGWAEGRWTHQGIDLNHNF 426

  Fly   591 PD-----QYGTDRF--------------------NKVTEPEVAAVMNWTLSLPFVLSANLHGGSL 630
            .|     .|..|..                    |....||..||:.|...:|||||||||||.|
  Rat   427 ADLNTQLWYAEDDGLVPHTVPNHHLPLPTYYTLPNATVAPETWAVIKWMKRIPFVLSANLHGGEL 491

  Fly   631 VANYPFDDNENDFNDPFMRLRNSSINGRKPNPTEDNALFKHLAGIYSNAHPTMY--LGQPCELFQ 693
            |.:||||            :..:....|:..||.|:|:|:.|:.:|:..:..|.  ..:||.  .
  Rat   492 VVSYPFD------------MTRTPWAARELTPTPDDAVFRWLSTVYAGTNRAMQDTDRRPCH--S 542

  Fly   694 NEFFPDG-ITNGAQWYSVTGGMQDWNYVRAGCLELTIEMGCDKFPKAAELSRYWEDHREPLLQFI 757
            .:|...| :.|||.|::|.|.|.|::|:...|.|:|:|:.|||||...||.:.||::::.||.::
  Rat   543 QDFSLHGNVINGADWHTVPGSMNDFSYLHTNCFEVTVELSCDKFPHEKELPQEWENNKDALLTYL 607

  Fly   758 EQVHCGIHGFVH---STIGTPIAGAVVRLDGANHSTYSQVFGDYWKLALPGRHNLTVLGDNYAPL 819
            |||..||.|.|.   :.:|  ||.||:.::|.||...:...||||:|..||.:.:|...:.|...
  Rat   608 EQVRMGITGVVRDKDTELG--IADAVIAVEGINHDVTTAWGGDYWRLLTPGDYVVTASAEGYHTA 670

  Fly   820 RMEVEVP-DVHPFEMRMDITLMPDDPQHWASANDFRIIENVVNTRYHTNPQVRARLAELENQ 880
            :....|. :..|......:|..|..          |::| ::.......|.:|.:|..|..|
  Rat   671 KQHCRVTFEEGPVPCNFLLTKTPKQ----------RLLE-LLAAGAKLPPDLRRKLEWLRGQ 721

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
svr	NP_996319.1	M14_CPD_I	40..334	CDD:349440	48/256 (19%)
		Peptidase_M14NE-CP-C_like	338..416	CDD:200604	16/78 (21%)
		M14_CP_N-E_like	456..759	CDD:349431	129/334 (39%)
		Peptidase_M14NE-CP-C_like	763..839	CDD:200604	23/79 (29%)
		Peptidase_M14NE-CP-C_like	1124..1190	CDD:473874
		CarboxypepD_reg	1223..1301	CDD:433354
Cpxm1	NP_001099981.1	FA58C	106..262	CDD:238014	49/265 (18%)
		M14_CPX_like	288..609	CDD:349441	129/334 (39%)
		Peptidase_M14NE-CP-C_like	613..689	CDD:200604	23/77 (30%)