DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment svr and Cpe

DIOPT Version :9

Sequence 1:	NP_001284744.1	Gene:	svr / 30998	FlyBaseID:	FBgn0004648	Length:	1439	Species:	Drosophila melanogaster
Sequence 2:	NP_037260.2	Gene:	Cpe / 25669	RGDID:	2394	Length:	476	Species:	Rattus norvegicus

Alignment Length:	405	Identity:	166/405 - (40%)
Similarity:	235/405 - (58%)	Gaps:	49/405 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly   454 YEHHNFTAMESYLRAISSSYPSLTRLYSIGKSVQGRDLWVLEIFATPGSHVPGVPEFKYVANMHG 518
            :|:|.:..:...|.::.....:::|:|::|:|.:||:|.|:|:...||.|.||.|||||:.||||
  Rat    51 FEYHRYPELREALVSVWLQCTAISRIYTVGRSFEGRELLVIELSDNPGVHEPGEPEFKYIGNMHG 115

  Fly   519 NEVVGKELLLILTKYMLERY--GNDDRITKLVNGTRMHFLYSMNPDGYE--ISIEGD-RTGGVGR 578
            ||.||:|||:.|.:|:...|  || :.|..|::.||:|.:.|:||||:|  .|..|: :...|||
  Rat   116 NEAVGRELLIFLAQYLCNEYQRGN-ETIVNLIHSTRIHIMPSLNPDGFEKAASQPGELKDWFVGR 179

  Fly   579 ANAHGIDLNRNFPDQYGTDRFNKVTE------------------------PEVAAVMNWTLSLPF 619
            :||.||||||||||   .||...|.|                        ||..||::|.:.:||
  Rat   180 SNAQGIDLNRNFPD---LDRIVYVNEKEGGPNNHLLKNLKKIVDQNSKLAPETKAVIHWIMDIPF 241

  Fly   620 VLSANLHGGSLVANYPFDDNENDFNDPFMRLRNSSINGRKPNPTEDNALFKHLAGIYSNAHPTMY 684
            |||||||||.||||||:|:.           |:.:.:.....|  |:|:|:.||..||:.:|.|.
  Rat   242 VLSANLHGGDLVANYPYDET-----------RSGTAHEYSSCP--DDAIFQSLARAYSSFNPVMS 293

  Fly   685 --LGQPCELFQNE-FFPDGITNGAQWYSVTGGMQDWNYVRAGCLELTIEMGCDKFPKAAELSRYW 746
              ...||....:: .|.||.|||..||||.|||||:||:.:.|.|:|:|:.|:|||....|..||
  Rat   294 DPNRPPCRKNDDDSSFVDGTTNGGAWYSVPGGMQDFNYLSSNCFEITVELSCEKFPPEETLKSYW 358

  Fly   747 EDHREPLLQFIEQVHCGIHGFVHSTIGTPIAGAVVRLDGANHSTYSQVFGDYWKLALPGRHNLTV 811
            ||::..|:.::||:|.|:.|||....|.|||.|.:.:||.:|...|...||||:|..||.:.||.
  Rat   359 EDNKNSLINYLEQIHRGVKGFVRDLQGNPIANATISVDGIDHDVTSAKDGDYWRLLAPGNYKLTA 423

  Fly   812 LGDNYAPLRMEVEVP 826
            ....|..:..:|.||
  Rat   424 SAPGYLAITKKVAVP 438

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
svr	NP_001284744.1	M14_CPD_I	40..334	CDD:199850
		Peptidase_M14NE-CP-C_like	338..416	CDD:200604
		M14_CP_N-E_like	456..759	CDD:199842	136/334 (41%)
		Peptidase_M14NE-CP-C_like	763..839	CDD:200604	26/64 (41%)
		CarbopepD_reg_2	1125..1202	CDD:290434
		CarboxypepD_reg	1223..1301	CDD:290350
Cpe	NP_037260.2	M14_CPE	53..371	CDD:349437	136/334 (41%)
Cpe	NP_037260.2	Peptidase_M14NE-CP-C_like	375..449	CDD:200604	26/64 (41%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	57	1.000	Domainoid score	I10592
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D101221at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11532
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	4.020