DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment svr and suro-1

DIOPT Version :9

Sequence 1:	NP_001284744.1	Gene:	svr / 30998	FlyBaseID:	FBgn0004648	Length:	1439	Species:	Drosophila melanogaster
Sequence 2:	NP_492177.2	Gene:	suro-1 / 172557	WormBaseID:	WBGene00011235	Length:	664	Species:	Caenorhabditis elegans

Alignment Length:	418	Identity:	102/418 - (24%)
Similarity:	152/418 - (36%)	Gaps:	134/418 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly   435 SEPPQKLKKQFNGFLTPTKY---EHHNFTAMESYLRAISSSYPSLTRLYSIGKSVQGRDLWVLEI 496
            |||...|.|.  |.|...||   ::.::..|..|:|.|...||.:.::..||.:.:|:.:..|:|
Worm   139 SEPDLDLTKV--GALKKAKYPFGDYASYADMVKYMRTIEFYYPRIAKIVRIGATHEGKPIEGLKI 201

  Fly   497 FATPGSH------VPGVPEFKYVANMHGNEVVGKELLLILTKYMLERYGNDDRITKLVNGTRMHF 555
            .|. .||      |.|        |:|..|.......|.....::..||.|.:||..|:....:.
Worm   202 GAR-SSHKKRAVWVDG--------NIHAREWASSHTALYFINQLVSEYGKDAQITNYVDTLDFYI 257

  Fly   556 LYSMNPDGYEISIEGDRTGGV---------------------GRANAHGIDLNRNFPDQ------ 593
            :..:||||||.:    ||..:                     |.....|:||||||...
Worm   258 VPCLNPDGYEYT----RTSPIPTVRLWRKNRSPELCRPSLWGGEKCCRGVDLNRNFRFHWAERGS 318

  Fly   594 ---------YGTDRFNKVTEPEVAAVMNWTLSLP--------FVLSANLHGGSLVANYPFDDNEN 641
                     :|.:.|   :|||..||.|: |:.|        ||   .||..:.:..||:...|.
Worm   319 SYEPCSNIYHGEEVF---SEPETRAVRNF-LATPEMKDRVDAFV---TLHSYAQLWIYPYSHEEQ 376

  Fly   642 DFNDPFMRLRNSSINGRKPNPTEDNALFKHLAGIYSNAHPTMY-LGQPCELFQNEFFPDGITNGA 705
            ::.:....||.::   ||        ....|:.:|.    |.| :|                .||
Worm   377 NYPEDIGELRKTA---RK--------AINRLSRVYG----TNYRMG----------------TGA 410

  Fly   706 QWYS-VTGGMQDW-----NYVRAGCLELTIEMGCDKFPKAAELSRYWEDHREPLLQFIEQVHCGI 764
            ...| ..||..||     |......:||..:|         |||..:..|::.|:....:.   .
Worm   411 DTLSPAAGGSDDWAKSALNVKYVYLIELRPQM---------ELSNGFILHKKELIPTAVET---F 463

  Fly   765 HGFVHSTIGTPIAGAVVRLDGANHSTYS 792
            .||      ..:..||:.|   |:||.|
Worm   464 EGF------REVVDAVLTL---NNSTSS 482

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
svr	NP_001284744.1	M14_CPD_I	40..334	CDD:199850
		Peptidase_M14NE-CP-C_like	338..416	CDD:200604
		M14_CP_N-E_like	456..759	CDD:199842	84/359 (23%)
		Peptidase_M14NE-CP-C_like	763..839	CDD:200604	9/30 (30%)
		CarbopepD_reg_2	1125..1202	CDD:290434
		CarboxypepD_reg	1223..1301	CDD:290350
suro-1	NP_492177.2	Propep_M14	39..110	CDD:280416
		M14_CP_A-B_like	161..473	CDD:199844	86/380 (23%)
		ShK	620..657	CDD:279838
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S4288
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.860