DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment svr and cpz

DIOPT Version :9

Sequence 1:	NP_001284744.1	Gene:	svr / 30998	FlyBaseID:	FBgn0004648	Length:	1439	Species:	Drosophila melanogaster
Sequence 2:	XP_012812537.1	Gene:	cpz / 100170588	XenbaseID:	XB-GENE-994183	Length:	662	Species:	Xenopus tropicalis

Alignment Length:	448	Identity:	179/448 - (39%)
Similarity:	246/448 - (54%)	Gaps:	58/448 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    33 SFLQQPHYASQEQLEDLFAGLEK--AYPNQ-AKVHFLGRSLEGRNLLALQISRNTRSRNLLTPPV 94
            :|:|..|::    ..|:...|:|  |..:| :|.:.:|||.||::|||::.|........|||..
Frog   186 TFIQFIHHS----YSDMVRVLKKTAARCSQISKTYSIGRSYEGKDLLAIEFSAQPGQHKALTPEF 246

  Fly    95 KYIANMHGDETVGRQLLVYMAQ-----YLLGNHERISDLGQLVNSTDIYLVPTMNPDGY--ALSQ 152
            :||.||||:|..||:||:|:||     |||||    |.:..|:|:|.|:|:|:||||||  |..:
Frog   247 RYIGNMHGNEVAGRELLIYLAQFLCSEYLLGN----SRIQTLINTTRIHLLPSMNPDGYEHAAEE 307

  Fly   153 EGNCESLPNYVGRGNAANIDLNRDFPDRLEQSHVHQLRAQSR---------------QPETAALV 202
            ........|  ||.||.||||||:|||...:.|.......:|               .||..|::
Frog   308 GAGYNGWTN--GRLNAQNIDLNRNFPDLTSEVHKIIRMPMARLDHMPIPESYWDGKIAPEAKAVM 370

  Fly   203 NWIVSKPFVLSANFHGGAVVASYPYDNSLAHNECCEESL---TPDDRVFKQLAHTYSDNHPIM-- 262
            .|:.|.|||:|.:.|||.:|.|||||.|   ....||.:   |||::||:.|..||...||||
Frog   371 KWMRSIPFVISGSLHGGDLVVSYPYDFS---RHPLEEKMFSPTPDEKVFQMLVKTYVAAHPIMSD 432

  Fly   263 ----RKGNNCNDSFSGGITNGAHWYELSGGMQDFNYAFSNCFELTIELSCCKYPAASTLPQEWQR 323
                |.|.|.|:  .|||.|||.||..||||.||:|..:||||||:||.|.|:|....|...||.
Frog   433 KSTSRCGGNFNN--KGGIINGAEWYSFSGGMADFSYLHTNCFELTLELGCEKFPTEDELYSIWQN 495

  Fly   324 NKASLLQLLRQAHIGIKGLVTDASGFPIADANVYVAGLEEKPMRTSKRGEYWRLLTPGLYSVHAS 388
            ||.::|.|:...|.||||.|.|..|.||..|.:.|.|:.. .:.|.:.|:|:|||.||.|.|.|.
Frog   496 NKEAMLSLIEMVHRGIKGFVKDEHGNPIKKARISVKGIRH-DITTGEDGDYFRLLIPGSYIVSAE 559

  Fly   389 AFGYQTSAPQQVRVTNDNQEALRLDFKLAPVETNFDGNFRKVKVERSEPPQKLKKQFN 446
            |||| :...:::.:.....:|.|:||.|..|:.. :..|.||      .|:.:.::|:
Frog   560 AFGY-SKVTKKITLPAKMLKAGRVDFALQRVDVK-NRKFHKV------APEDIYERFD 609

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
svr	NP_001284744.1	M14_CPD_I	40..334	CDD:199850	137/327 (42%)
		Peptidase_M14NE-CP-C_like	338..416	CDD:200604	31/77 (40%)
		M14_CP_N-E_like	456..759	CDD:199842
		Peptidase_M14NE-CP-C_like	763..839	CDD:200604
		CarbopepD_reg_2	1125..1202	CDD:290434
		CarboxypepD_reg	1223..1301	CDD:290350
cpz	XP_012812537.1	CRD_FZ	46..169	CDD:382974
		M14_CPZ	192..506	CDD:349439	138/328 (42%)
		Peptidase_M14NE-CP-C_like	510..586	CDD:200604	31/77 (40%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	57	1.000	Domainoid score	I10678
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D101221at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11532
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	5.020