DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG17896 and Aldh

DIOPT Version :9

Sequence 1:	NP_569845.2	Gene:	CG17896 / 30995	FlyBaseID:	FBgn0023537	Length:	520	Species:	Drosophila melanogaster
Sequence 2:	NP_001260290.1	Gene:	Aldh / 34256	FlyBaseID:	FBgn0012036	Length:	520	Species:	Drosophila melanogaster

Alignment Length:	510	Identity:	150/510 - (29%)
Similarity:	252/510 - (49%)	Gaps:	25/510 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 LIGAEARHLAK--RSYSS-----AAPT---TKLFIDGKFVESKTNEWIDVHDPATNQVVTRVPKA 60
            |:.::|::.|.  .:|||     ..|.   |.:||:.::.:||:.:..:..:|.|.:|:..:..|
  Fly    10 LLRSQAKNFAAAVANYSSLPQPQTTPDILYTGVFINNEWHKSKSGKIFETINPTTAEVIAEIQCA 74

  Fly    61 TQAEMQAALESNKKAFR---SWSNQSILTRQQVMFKLQALIKENMGELAKNITKEQGKTLADAEG 122
            .:.::..|:::.:.||:   .|.......|.:::::|..|::.:...||...|.:.||..:.:..
  Fly    75 DKEDIDIAVQAARNAFKLGSPWRRMDASERGRLLYRLADLMERDQVYLASLETLDNGKPYSMSYN 139

  Fly   123 -DVLRGLQVVEHCCSIPSLQMGETVANVARDMDTYSLVLPLGVTAGVAPFNFPAMIPLWMFPVAI 186
             |:...::.:.:.........|:|:. :..|..||:...|:||...:.|:|||.::..|....|:
  Fly   140 VDLPTAIKNLRYFAGWADKNHGKTIP-MDGDFFTYTRHEPVGVCGQIIPWNFPILMMAWKLGPAL 203

  Fly   187 TTGNTMLLKPSERVPGATMLLMELLNEAGCPPGVVNVIHGQHDAVNFICDAPEIKAVSFVGSDQA 251
            .||||::|||:|:.....:.:.:|:.|||.|.|||||:.|...|...:.:..::..|:|.||...
  Fly   204 ATGNTIVLKPAEQTSLTALYIAQLVKEAGFPEGVVNVVPGFGTAGAALANHCDVDKVAFTGSTDV 268

  Fly   252 GKYIYERAGK-NGKRVQSNMGAKNHGIILGDANKENTLNQLAGAAFGAAGQRCMALSTAVFVGDA 315
            ||.|...:|. |.|||...:|.|:..|||.|.:.:..:.......|...||.|.| .:..||.|.
  Fly   269 GKLIQLASGNTNLKRVTLELGGKSPNIILSDTDMDYAVETAHFGLFFNMGQCCCA-GSRTFVEDK 332

  Fly   316 --QAWIPDLVERAQKLKVNAGHVPGTDVGPVISAASRQRINDLIESGVKEGAKLILDGRKITVPG 378
              ..::....|||:|..|.......|:.||.::....::|..:|::|.|:||||:..|.:   |.
  Fly   333 IYDEFVERSAERAKKRTVGNPFDLNTEQGPQVNEEQMEKILGMIKTGKKQGAKLVAGGSR---PE 394

  Fly   379 YEDGYFVGPTILSDVTPSMKCYTEEIFGPVLVILKADTLDDAIGIVNANPYGNGTAVFTTNGAAA 443
            ...||||.||:.:||...|....|||||||..:::...||:.|...|.:.||...||||.:...|
  Fly   395 GLPGYFVQPTVFADVQDDMTIAREEIFGPVQQLIRFKKLDEVIERANNSEYGLAAAVFTKDLDKA 459

  Fly   444 RKFVNEIDAGQVGVNVPIPVPLPMFSFTGTRGSFRGDHHFYGKQGIKFYTQTKTV 498
            ...|..:.||.|.||. ..|......|.|.:.|..|..:  |:..:..||:.|:|
  Fly   460 NYIVGGLRAGTVWVNT-YNVLAAQAPFGGYKMSGHGREN--GEYALSNYTEVKSV 511

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17896	NP_569845.2	ALDH_F6_MMSDH	26..502	CDD:143404	143/480 (30%)
Aldh	NP_001260290.1	PLN02466	9..512	CDD:215259	150/510 (29%)
Aldh	NP_001260290.1	ALDH_F1AB_F2_RALDH1	34..514	CDD:143459	144/486 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45454107
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.840