DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG3156 and ABCB26

DIOPT Version :9

Sequence 1:	NP_569844.2	Gene:	CG3156 / 30994	FlyBaseID:	FBgn0023536	Length:	692	Species:	Drosophila melanogaster
Sequence 2:	NP_177218.3	Gene:	ABCB26 / 843398	AraportID:	AT1G70610	Length:	700	Species:	Arabidopsis thaliana

Alignment Length:	639	Identity:	204/639 - (31%)
Similarity:	342/639 - (53%)	Gaps:	65/639 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    67 WWCMRRGFAQSSKWLARNAKANLPTAVGAGIVPAPVKMGRSQYGRLLSLTKSEKWVLTAGIGCLV 131
            ||                   :....|....:..||.:.|: ..|:..|...::||:.|....|:
plant   103 WW-------------------SFSDEVDGRFIAKPVTVWRA-LSRMWELVAEDRWVIFAAFSTLI 147

  Fly   132 VSSAITMSVPLFLGKVIDVVFNKSGMDSAAMAKLGEYSV------LLFGIFVLGGFANFARVHLF 190
            |::...:::|.||            ..|...|:.|:.:|      ||..:.|..|..:..|...|
plant   148 VAALSEITIPHFL------------TASIFSAQSGDIAVFHRNVKLLVTLCVTSGICSGIRGCFF 200

  Fly   191 GNAALRIVRSLRSRLYRSMLMQEVGWFDTKGTGELINRLSNDTLMVGTSLSQNVSDGLRSVAMIG 255
            |.|.:.:|:.:|..||.::|.|::.:||::..|:|.:||.:|...|...:..:::...|:|..
plant   201 GIANMILVKRMRETLYSTLLFQDISFFDSQTVGDLTSRLGSDCQQVSRVIGNDLNMIFRNVLQ-- 263

  Fly   256 VGTGMMIY---TSPQLAAVSALVVPAMAGMAIVYGRYVRRITKVELDKYAEIMKFAEERFGNVKT 317
             |||.:||   .|..|...:.::...:|.:..|||.|.::..|:..:..|...:.|:|.:..::|
plant   264 -GTGALIYLLILSWPLGLCTLVICCILAAVMFVYGMYQKKTAKLIQEITASANEVAQETYSLMRT 327

  Fly   318 VKTFCREQQEVAAFDGKLDEALQIGYKETRARAIFFGLTGFCGNFI-----IISVLYYGGTLVLQ 377
            |:.:..|:||...::..|.....|..:::.|    :|:..:..|.:     ||:|| .||..:|.
plant   328 VRVYGTEKQEFKRYNHWLQRLADISLRQSAA----YGIWNWSFNTLYHATQIIAVL-VGGLSILA 387

  Fly   378 DSLTIGALTAFMLYAGYVAISMNGLSNFYSQLNKGIGASERIWEILDRECSIP-IDKGVVPLEKP 441
            ..:|...||.|:||:.::..:...:.:..|.|.:.:||||::::::|.:.|.. |.|| ..|::.
plant   388 GQITAEQLTKFLLYSEWLIYATWWVGDNLSSLMQSVGASEKVFQMMDLKPSDQFISKG-TRLQRL 451

  Fly   442 VGEVGFQNVFFTFPTRPESAVLTDFSLNLMPGTTTAVVGRSGSGKTTIALLMLRLYDPQGGTVHL 506
            .|.:.|.:|.|::|:|.|.||:.:.::::.||...|:||.|||||:|:..|:|:||:|..|.:.|
plant   452 TGHIEFVDVSFSYPSRDEVAVVQNVNISVHPGEVVAIVGLSGSGKSTLVNLLLQLYEPTSGQILL 516

  Fly   507 DGIDLRTVNPQWLRNNIGAVSQEPVLFSCSIRENILYGANPGETPSPERLQQVIEDANVSQFTDQ 571
            ||:.|:.::.:|||..||.|.|||.||...|..||.||.:  ...|.|.:....:.|....|...
plant   517 DGVPLKELDVKWLRQRIGYVGQEPKLFRTDISSNIKYGCD--RNISQEDIISAAKQAYAHDFITA 579

  Fly   572 LPDGLDTLVGQRGMMLSGGQKQRVAIARALIKNPAILILDEATSALDAVSENLVQNALDNL---- 632
            ||:|.:|:|...  :||||||||:|||||::::|.|||||||||||||.||:.|:..|.::
plant   580 LPNGYNTIVDDD--LLSGGQKQRIAIARAILRDPRILILDEATSALDAESEHNVKGVLRSIGNDS 642

  Fly   633 IQGRTVLTIAHRLSTIRNADQIAVLSDGKIVEQGSYNELMGIQEGVFRELVASQ 686
            ...|:|:.||||||||:.||:|..:..|::||.||:.||:. ::|::..|...|
plant   643 ATKRSVIVIAHRLSTIQAADRIVAMDSGRVVEMGSHKELLS-KDGLYARLTKRQ 695

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3156	NP_569844.2	MdlB	106..687	CDD:224055	199/600 (33%)
		ABC_membrane	127..395	CDD:279056	72/281 (26%)
		ABC_MTABC3_MDL1_MDL2	447..686	CDD:213216	107/242 (44%)
ABCB26	NP_177218.3	3a01208	76..691	CDD:273363	202/633 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0058
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54509
OrthoDB	1	1.010	-	-		D684058at2759
OrthoFinder	1	1.000	-	-		FOG0000243
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.830