Protein Alignment CG3156 and Abcb11

DIOPT Version :10

• Sequence 1: NP_569844.2
• Gene: CG3156 / 30994
• FlyBaseID: FBgn0023536
• Length: 692
• Species: Drosophila melanogaster
• Sequence 2: NP_113948.1
• Gene: Abcb11 / 83569
• RGDID: 619930
• Length: 1321
• Species: Rattus norvegicus
• Alignment Length: 532
• Identity: 201/532 - (37%)
• Similarity: 297/532 - (55%)
• Gaps: 22/532 - (4%)

  Fly   166 GEYSVLLFGIFVLGGFANFARVHLFGNAALRIVRSLRSRLYRSMLMQEVGWFDTKGTGELINRLS 230
            |.|:.:...:.:||.|    ::.|:.....|.:|.:|...:|.::..|:||||....|||.:|.:
  Rat   143 GIYAGVGMTVLILGYF----QIRLWVITGARQIRRMRKIYFRRIMRMEIGWFDCTSVGELNSRFA 203

  Fly   231 NDTLMVGTSLSQNVSDGLR--SVAMIGVGTGMMIYTSPQLAAVSALVVPAMAGMAIVYGRYVRRI 293
            :|...:..:::..::..|:  |.||.|:..|  .|...:|..|...|.|.:...|.|.|..:.:.
  Rat   204 DDIEKINDAIADQLAHFLQRMSTAMCGLLLG--FYRGWKLTLVILAVSPLIGIGAAVIGLSIAKF 266

  Fly   294 TKVELDKYAEIMKFAEERFGNVKTVKTFCREQQEVAAFDGKLDEALQIGYKETRARAIFFG---- 354
            |::||..||:....|:|...:::||..|..|.:||..::..|..|.:.|..:......|.|
  Rat   267 TELELKAYAKAGSIADEVLSSIRTVAAFGGENKEVERYEKNLVFAQRWGIWKGMVMGFFTGYMWC 331

  Fly   355 LTGFCGNFIIISVLYYGGTLVL-QDSLTIGALTAFMLYAGYVAISMNGLSNFYSQLNKGIGASER 418
            |..||    .....:||.|||| ::..|.|.|....|.....|:::...|:.....:.|..|:..
  Rat   332 LIFFC----YALAFWYGSTLVLDEEEYTPGTLVQIFLCVILAAMNIGHASSCLEIFSTGCSAATN 392

  Fly   419 IWEILDRECSIPIDKG-VVPLEKPVGEVGFQNVFFTFPTRPESAVLTDFSLNLMPGTTTAVVGRS 482
            |::.:||:..|....| ...|::..||:.|.||.|.:|:||:..:|.:.|:.:.||.|||:||.|
  Rat   393 IFQTIDRQPVIDCMSGDGYKLDRIKGEIEFHNVTFHYPSRPDVKILDNLSMVIKPGETTALVGSS 457

  Fly   483 GSGKTTIALLMLRLYDPQGGTVHLDGIDLRTVNPQWLRNNIGAVSQEPVLFSCSIRENILYGANP 547
            |:||:|...|:.|.|||..|.|.|||.|:|::|.:|||:.||.|.|||||||.:|.|||.:|.
  Rat   458 GAGKSTALQLIQRFYDPCEGMVTLDGHDIRSLNIRWLRDQIGIVEQEPVLFSTTIAENIRFGR-- 520

  Fly   548 GETPSPERLQQVIEDANVSQFTDQLPDGLDTLVGQRGMMLSGGQKQRVAIARALIKNPAILILDE 612
             |..:.|.:.|..:|||...|...||...|||||:.|..:|||||||||||||||:||.||:||.
  Rat   521 -EDATMEDIVQAAKDANAYNFIMALPQQFDTLVGEGGGQMSGGQKQRVAIARALIRNPKILLLDM 584

  Fly   613 ATSALDAVSENLVQNALDNLIQGRTVLTIAHRLSTIRNADQIAVLSDGKIVEQGSYNELMGIQEG 677
            ||||||..||..||.||:.:..|.|::::||||||:|.||.|.....|..||:|::.||:. ::|
  Rat   585 ATSALDNESEARVQEALNKIQHGHTIISVAHRLSTVRAADVIIGFEHGVAVERGTHEELLE-RKG 648

  Fly   678 VFRELVASQAFG 689
            |:..||..|:.|
  Rat   649 VYFMLVTLQSQG 660

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3156	NP_569844.2	MdlB	103..687	CDD:440747	199/528 (38%)
Abcb11	NP_113948.1	PTZ00265	150..1314	CDD:240339	199/525 (38%)
		Interaction with HAX1. /evidence=ECO:0000269|PubMed:15159385	651..674		4/10 (40%)