DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG3156 and ABCB2

DIOPT Version :9

Sequence 1:	NP_569844.2	Gene:	CG3156 / 30994	FlyBaseID:	FBgn0023536	Length:	692	Species:	Drosophila melanogaster
Sequence 2:	NP_194326.2	Gene:	ABCB2 / 828702	AraportID:	AT4G25960	Length:	1273	Species:	Arabidopsis thaliana

Alignment Length:	689	Identity:	217/689 - (31%)
Similarity:	351/689 - (50%)	Gaps:	73/689 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 LRVRKSSQIRLSTSYNHHLGRCLHHRTARSLQHSLPPPNRYHSHLHPTLRMPWWCMRRGFAQSSK 79
            ||:::::.::.:.|.|..|.|          .||:    :|...|..|        |..|....:
plant   636 LRLQETASLQRNPSLNRTLSR----------PHSI----KYSRELSRT--------RSSFCSERE 678

  Fly    80 WLARNAKANLPTAVGAGIVPAPVKMGRSQYGRLLSLTKSEKWVLTAGIGCLVVSSAITMSVPLF- 143
            .:.|...|:            |.|..:...|||.|:.:.:......|..|..::.:   .:|||
plant   679 SVTRPDGAD------------PSKKVKVTVGRLYSMIRPDWMYGVCGTICAFIAGS---QMPLFA 728

  Fly   144 LGKVIDVVFNKSGMDSAAMAKLGEYSVLLFGIFVLGGFANFARVHLFGNAALRIVRSLRSRLYRS 208
            ||....:|...||.|. ...::.:.::|.....|:...........||....|:...:|..::|:
plant   729 LGVSQALVSYYSGWDE-TQKEIKKIAILFCCASVITLIVYTIEHICFGTMGERLTLRVRENMFRA 792

  Fly   209 MLMQEVGWFD--TKGTGELINRLSNDTLMVGTSLSQNVSDGLRSVAMIGVGTGMMIYTSPQLAAV 271
            :|..|:||||  ...:..|.:||.:|..::.|.:....:..|:::.::.....:....:.:|..|
plant   793 ILKNEIGWFDEVDNTSSMLASRLESDATLLKTIVVDRSTILLQNLGLVVTSFIIAFILNWRLTLV 857

  Fly   272 SALVVPAMAGMAIVYGRYVRRITKV----ELDK-YAEIMKFAEERFGNVKTVKTFCREQQEVAAF 331
            .....|     .::.|....::...    :|:| |.:....|.|...|::||..||.|::.:..:
plant   858 VLATYP-----LVISGHISEKLFMQGYGGDLNKAYLKANMLAGESVSNIRTVAAFCAEEKILELY 917

  Fly   332 DGKLDEALQIGYKETRARAIFFGLTGFCGNFIIIS---VLYYGGTLVLQDSLTIG---ALTAFML 390
            ..:|.|..:..::..:...:|:|::.|   ||..|   .|:||.||:  |....|   .:..||:
plant   918 SRELLEPSKSSFRRGQIAGLFYGVSQF---FIFSSYGLALWYGSTLM--DKGLAGFKSVMKTFMV 977

  Fly   391 YAGYVAISMNGLSNFYSQLNKGIGASERIWEILDRECSIPIDKGVVPLEKPVGEVGFQNVFFTFP 455
            .. ..|::|.........|.||......::|||||:..| :.:....|....|.:..:.|.|::|
plant   978 LI-VTALAMGETLALAPDLLKGNQMVASVFEILDRKTQI-VGETSEELNNVEGTIELKGVHFSYP 1040

  Fly   456 TRPESAVLTDFSLNLMPGTTTAVVGRSGSGKTTIALLMLRLYDPQGGTVHLDGIDLRTVNPQWLR 520
            :||:..:..||.|.:..|.:.|:||:|||||:::..|:||.|||..|.|.::|.|::.::.:.||
plant  1041 SRPDVVIFRDFDLIVRAGKSMALVGQSGSGKSSVISLILRFYDPTAGKVMIEGKDIKKLDLKALR 1105

  Fly   521 NNIGAVSQEPVLFSCSIRENILYGANPGETPSPERLQQVIED---ANVSQFTDQLPDGLDTLVGQ 582
            .:||.|.|||.||:.:|.|||||| |.|.:.|     :|:|.   ||...|...||:|..|.||:
plant  1106 KHIGLVQQEPALFATTIYENILYG-NEGASQS-----EVVESAMLANAHSFITSLPEGYSTKVGE 1164

  Fly   583 RGMMLSGGQKQRVAIARALIKNPAILILDEATSALDAVSENLVQNALDNLIQGRTVLTIAHRLST 647
            ||:.:||||:||:|||||::||||||:|||||||||..||.:||.|||.|:..||.:.:||||||
plant  1165 RGVQMSGGQRQRIAIARAILKNPAILLLDEATSALDVESERVVQQALDRLMANRTTVVVAHRLST 1229

  Fly   648 IRNADQIAVLSDGKIVEQGSYNELMGIQEGVFRELVASQ 686
            |:|||.|:||..||||||||:.:|:..:.|.:.:|::.|
plant  1230 IKNADTISVLHGGKIVEQGSHRKLVLNKSGPYFKLISLQ 1268

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3156	NP_569844.2	MdlB	106..687	CDD:224055	200/598 (33%)
		ABC_membrane	127..395	CDD:279056	61/281 (22%)
		ABC_MTABC3_MDL1_MDL2	447..686	CDD:213216	120/241 (50%)
ABCB2	NP_194326.2	PTZ00265	76..1269	CDD:240339	217/689 (31%)
		ABC_membrane	86..349	CDD:279056
		ABC_MTABC3_MDL1_MDL2	401..639	CDD:213216	2/2 (100%)
		ABC_membrane	714..983	CDD:279056	61/283 (22%)
		ABC_MTABC3_MDL1_MDL2	1030..1268	CDD:213216	120/243 (49%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100059
Panther	1	1.100	-	-	O	PTHR24221
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.910