DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG3156 and ABCB9

DIOPT Version :9

Sequence 1:	NP_569844.2	Gene:	CG3156 / 30994	FlyBaseID:	FBgn0023536	Length:	692	Species:	Drosophila melanogaster
Sequence 2:	NP_001328203.1	Gene:	ABCB9 / 827530	AraportID:	AT4G18050	Length:	1246	Species:	Arabidopsis thaliana

Alignment Length:	596	Identity:	208/596 - (34%)
Similarity:	328/596 - (55%)	Gaps:	46/596 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly   117 KSEKWVLTAGIGCLVVSSAITMSVPLFLGKVIDVVFNKSGMDSAAMAKLGEYSVLLFGIFVLGGF 181
            |::..::|.|......:......:.|..|::|: .|..:..|. .:.::.:.:|....:.|....
plant    37 KTDVVLMTVGTIAAAGNGLTQPFMTLIFGQLIN-AFGTTDPDH-MVREVWKVAVKFIYLAVYSCV 99

  Fly   182 ANFARVHLFGNAALRIVRSLRSRLYRSMLMQEVGWFDTK-GTGELINRLSNDTLMVGTSLSQNVS 245
            ..|.:|..:.....|...::|....:::|.|::|:|||: .|||:|.|:|.||:::..::.:.|.
plant   100 VAFLQVSCWMVTGERQSATIRGLYLKTILRQDIGYFDTETNTGEVIGRMSGDTILIQDAMGEKVG 164

  Fly   246 DGLRSVAMIGVGTGMMIYTSPQLAAVSA----LVVPAMAGMAIVYGRYVRRITKVELDKYAEIMK 306
            ...:.:.....|..:..|..|.||.|..    |:|.|.|.|:::..:...|....    |||...
plant   165 KFTQLLCTFLGGFAIAFYKGPLLAGVLCSCIPLIVIAGAAMSLIMSKMAGRGQVA----YAEAGN 225

  Fly   307 FAEERFGNVKTVKTFCREQQEVAAFDGKLDEALQIGYKE-------------TRARAIF--FGLT 356
            ..|:..|.::||..|..|:|....::.|    |:|.||.             |....||  :||.
plant   226 VVEQTVGAIRTVVAFTGEKQATEKYESK----LEIAYKTVVQQGLISGFGLGTMLAVIFCSYGLA 286

  Fly   357 GFCGNFIIISVLYYGGTLVLQDSLTIGALTAFMLYAGYVAISMNGLSNFYSQLNKGIGASERIWE 421
            .:.|..:|:...|.||.::   ::....||..| ..|..:.|:|..:       .|..|:.:::|
plant   287 VWYGAKLIMEKGYNGGQVI---NVIFAVLTGGM-SLGQTSPSLNAFA-------AGRAAAFKMFE 340

  Fly   422 ILDRECSI-PIDKGVVPLEKPVGEVGFQNVFFTFPTRPESAVLTDFSLNLMPGTTTAVVGRSGSG 485
            .:.|...| ..|.....||...|::..::|:|.:|.||:..:...|||.:..|.|.|:||:||||
plant   341 TIKRSPKIDAYDMSGSVLEDIRGDIELKDVYFRYPARPDVQIFAGFSLFVPNGKTVALVGQSGSG 405

  Fly   486 KTTIALLMLRLYDPQGGTVHLDGIDLRTVNPQWLRNNIGAVSQEPVLFSCSIRENILYGANPGET 550
            |:|:..|:.|.|||:.|.|.:|.|||:.:..:|:|:.||.||||||||:.:|:|||.||.   |.
plant   406 KSTVISLIERFYDPESGQVLIDNIDLKKLQLKWIRSKIGLVSQEPVLFATTIKENIAYGK---ED 467

  Fly   551 PSPERLQQVIEDANVSQFTDQLPDGLDTLVGQRGMMLSGGQKQRVAIARALIKNPAILILDEATS 615
            .:.:.::..||.||.::|.|:||.||||:||:.|..:|||||||:|||||::|||.||:||||||
plant   468 ATDQEIRTAIELANAAKFIDKLPQGLDTMVGEHGTQMSGGQKQRLAIARAILKNPKILLLDEATS 532

  Fly   616 ALDAVSENLVQNALDNLIQGRTVLTIAHRLSTIRNADQIAVLSDGKIVEQGSYNELMGIQEGVFR 680
            ||||.||.:||:||.||:..||.:.:||||:|||.||.|||:..|||||:|:::|::...||.:.
plant   533 ALDAESERIVQDALVNLMSNRTTVVVAHRLTTIRTADVIAVVHQGKIVEKGTHDEMIQDPEGAYS 597

  Fly   681 ELVASQAFGSR 691
            :||..|. ||:
plant   598 QLVRLQE-GSK 607

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3156	NP_569844.2	MdlB	106..687	CDD:224055	205/590 (35%)
		ABC_membrane	127..395	CDD:279056	67/287 (23%)
		ABC_MTABC3_MDL1_MDL2	447..686	CDD:213216	124/238 (52%)
ABCB9	NP_001328203.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100059
Panther	1	1.100	-	-	O	PTHR24221
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.910