DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG3156 and ABCB19

DIOPT Version :9

Sequence 1:	NP_569844.2	Gene:	CG3156 / 30994	FlyBaseID:	FBgn0023536	Length:	692	Species:	Drosophila melanogaster
Sequence 2:	NP_189528.1	Gene:	ABCB19 / 822519	AraportID:	AT3G28860	Length:	1252	Species:	Arabidopsis thaliana

Alignment Length:	619	Identity:	215/619 - (34%)
Similarity:	354/619 - (57%)	Gaps:	39/619 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    95 AGIVPAPVKMGRSQ---YGRLLSLTKSEKWVL--TAGIGCLVVSSAITMSVPLF---LGKVIDVV 151
            |..|||..:..:.|   :.:|.|......::|  ...:|.:|..|    |:|:|   .|:::: .
plant     9 AKTVPAEAEKKKEQSLPFFKLFSFADKFDYLLMFVGSLGAIVHGS----SMPVFFLLFGQMVN-G 68

  Fly   152 FNKSGMDSAAMA-KLGEYSVLLFGIFVLGGFANFARVHLFGNAALRIVRSLRSRLYRSMLMQEVG 215
            |.|:.||...|. ::..||:....:.::..|:::|.:..:..:..|.|.:||.:...::|.|:||
plant    69 FGKNQMDLHQMVHEVSRYSLYFVYLGLVVCFSSYAEIACWMYSGERQVAALRKKYLEAVLKQDVG 133

  Fly   216 WFDTKG-TGELINRLSNDTLMVGTSLSQNVSDGLRSVAMIGVGTGMMIYTSPQLAAVSALVVPAM 279
            :|||.. ||:::..:|.|||:|..::|:.|.:.:..::....|..:...::.:||.:|..|:|.:
plant   134 FFDTDARTGDIVFSVSTDTLLVQDAISEKVGNFIHYLSTFLAGLVVGFVSAWKLALLSVAVIPGI 198

  Fly   280 AGMAIVYGRYVRRITKVELDKYAEIMKFAEERFGNVKTVKTFCREQQEVAAFDGKLDEALQIGYK 344
            |....:|...:..||....:.||.....||:....|:||.::..|.:.:.|:...:...|::|||
plant   199 AFAGGLYAYTLTGITSKSRESYANAGVIAEQAIAQVRTVYSYVGESKALNAYSDAIQYTLKLGYK 263

  Fly   345 ETRARAIFFGLT-GF-CGNFIIISVLYYGGTLVLQDSLTIG--ALTA-FMLYAGYVAI--SMNGL 402
            ...|:.:..|.| |. |.::.:  |.:|.|..: ::..|.|  |.|| |....|.:::  |.:.|
plant   264 AGMAKGLGLGCTYGIACMSWAL--VFWYAGVFI-RNGQTDGGKAFTAIFSAIVGGMSLGQSFSNL 325

  Fly   403 SNFYSQLNKGIGASERIWEILDRECSI---PIDKGVVPLEKPVGEVGFQNVFFTFPTRPESAVLT 464
            ..|    :||..|..::.||:::..:|   |:|...  |::..|.:.|::|.|::|:||:..:..
plant   326 GAF----SKGKAAGYKLMEIINQRPTIIQDPLDGKC--LDQVHGNIEFKDVTFSYPSRPDVMIFR 384

  Fly   465 DFSLNLMPGTTTAVVGRSGSGKTTIALLMLRLYDPQGGTVHLDGIDLRTVNPQWLRNNIGAVSQE 529
            :|::....|.|.||||.|||||:|:..|:.|.|||..|.:.|||::::|:..::||..||.|:||
plant   385 NFNIFFPSGKTVAVVGGSGSGKSTVVSLIERFYDPNSGQILLDGVEIKTLQLKFLREQIGLVNQE 449

  Fly   530 PVLFSCSIRENILYGANPGETPSPERLQQVIEDANVSQFTDQLPDGLDTLVGQRGMMLSGGQKQR 594
            |.||:.:|.|||||| .|..|  ...::.....||...|...||.|.||.||:||:.||||||||
plant   450 PALFATTILENILYG-KPDAT--MVEVEAAASAANAHSFITLLPKGYDTQVGERGVQLSGGQKQR 511

  Fly   595 VAIARALIKNPAILILDEATSALDAVSENLVQNALDNLIQGRTVLTIAHRLSTIRNADQIAVLSD 659
            :|||||::|:|.||:||||||||||.||::||.|||.::.|||.:.:||||.||||.|.|||:..
plant   512 IAIARAMLKDPKILLLDEATSALDASSESIVQEALDRVMVGRTTVVVAHRLCTIRNVDSIAVIQQ 576

  Fly   660 GKIVEQGSYNELMGIQEGVFRELVASQAF-GSRN 692
            |::||.|::.||:. :.|.:..|:..|.. |:|:
plant   577 GQVVETGTHEELIA-KSGAYASLIRFQEMVGTRD 609

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3156	NP_569844.2	MdlB	106..687	CDD:224055	208/600 (35%)
		ABC_membrane	127..395	CDD:279056	74/277 (27%)
		ABC_MTABC3_MDL1_MDL2	447..686	CDD:213216	117/238 (49%)
ABCB19	NP_189528.1	PTZ00265	17..1247	CDD:240339	211/611 (35%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	82	1.000	Domainoid score	I2913
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100059
Panther	1	1.100	-	-	O	PTHR24221
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.910