Protein Alignment CG3156 and Abcb5

DIOPT Version :9

• Sequence 1: NP_569844.2
• Gene: CG3156 / 30994
• FlyBaseID: FBgn0023536
• Length: 692
• Species: Drosophila melanogaster
• Sequence 2: NP_084237.1
• Gene: Abcb5 / 77706
• MGIID: 1924956
• Length: 1255
• Species: Mus musculus
• Alignment Length: 583
• Identity: 189/583 - (32%)
• Similarity: 307/583 - (52%)
• Gaps: 24/583 - (4%)

  Fly   122 VLTAGIGCLVVSSAITMSVPLFLGKVIDVVFN---------KSGMDSAAMAKLGEYSVLLFGIFV 177
            ::|.||...:::.|....:.|.||::.|.:.|         |....|....||.| .:::..::.
Mouse    48 LMTLGILASMINGATVPLMSLVLGEISDHLINGCLVQTNRTKYQNCSQTQEKLNE-DIIVLTLYY 111

  Fly   178 LG-GFA----NFARVHLFGNAALRIVRSLRSRLYRSMLMQEVGWFDTKGTGELINRLSNDTLMVG 237
            :| |.|    .:.::..:...|.|....:|.:.:.|:|.|::.|||.....||..|::.|...:.
Mouse   112 IGIGAAALIFGYVQISFWVITAARQTTRIRKQFFHSILAQDISWFDGSDICELNTRMTGDINKLC 176

  Fly   238 TSLSQNVSDGLRSVAMIGVGTGMMIYTSPQLAAVSALVVPAMAGMAIVYGRYVRRITKVELDKYA 302
            ..:...:....::::...:|..:.:..|.:|:.|.....|.:...:.:..|.:..:|..|||.|:
Mouse   177 DGIGDKIPLMFQNISGFSIGLVISLIKSWKLSLVVLSTSPLIMASSALCSRMIISLTSKELDAYS 241

  Fly   303 EIMKFAEERFGNVKTVKTFCREQQEVAAFDGKLDEALQIGYKETRARAIFFGLTGFCGNFIIISV 367
            :....|||...:::||..|..:::|:..:...|.:|...|.|...|..:..|...|..|......
Mouse   242 KAGAVAEEALSSIQTVTAFGAQEKEIQRYTQHLKDAKDAGIKRATASKLSLGAVYFFMNGAYGLA 306

  Fly   368 LYYGGTLVL--QDSLTIGALTAFMLYAGYVAISMNGLSNFYSQLNKGIGASERIWEILDRECSIP 430
            .:||.:|:.  :...|||.:.|......:.:..:..::..........||:..|::::|::.:|.
Mouse   307 FWYGTSLIFGGEPGYTIGTILAVFFSVIHSSYCIGSVAPHLETFTVARGAAFNIFQVIDKKPNID 371

  Fly   431 --IDKGVVPLEKPVGEVGFQNVFFTFPTRPESAVLTDFSLNLMPGTTTAVVGRSGSGKTTIALLM 493
              ...|.|| |...|.:.|:||.|::|:||.:.||...:|.:..|.|.|:||.|||||:|...|:
Mouse   372 NFSTAGFVP-ECIEGNIEFKNVSFSYPSRPSAKVLKGLNLKIKAGETVALVGPSGSGKSTTVQLL 435

  Fly   494 LRLYDPQGGTVHLDGIDLRTVNPQWLRNNIGAVSQEPVLFSCSIRENILYGANPGETPSPERLQQ 558
            .|||||:.|.:.:|..|:|..|.:..|..||.|.||||||..:|..||.:|.   |....:.::|
Mouse   436 QRLYDPEDGCITVDENDIRAQNVRHYREQIGVVRQEPVLFGTTIGNNIKFGR---EGVGEKEMEQ 497

  Fly   559 VIEDANVSQFTDQLPDGLDTLVGQRGMMLSGGQKQRVAIARALIKNPAILILDEATSALDAVSEN 623
            ...:||...|....|...:||||::|..:|||||||:||||||::||.||||||||||||..||:
Mouse   498 AAREANAYDFIMAFPKKFNTLVGEKGAQMSGGQKQRIAIARALVRNPKILILDEATSALDTESES 562

  Fly   624 LVQNALDNLIQGRTVLTIAHRLSTIRNADQIAVLSDGKIVEQGSYNELMGIQEGVFRELVASQ 686
            |||.||:...:|||.:.:||||||||.||.|..:.||.:||:|::.|||. ::|::..|..:|
Mouse   563 LVQTALEKASKGRTTIVVAHRLSTIRGADLIVTMKDGMVVEKGTHAELMA-KQGLYYSLAMAQ 624

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3156	NP_569844.2	MdlB	106..687	CDD:224055	189/583 (32%)
		ABC_membrane	127..395	CDD:279056	61/283 (22%)
		ABC_MTABC3_MDL1_MDL2	447..686	CDD:213216	115/238 (48%)
Abcb5	NP_084237.1	PTZ00265	48..1250	CDD:240339	189/583 (32%)
		ABC_membrane	53..334	CDD:279056	61/281 (22%)
		ABC_MTABC3_MDL1_MDL2	387..624	CDD:213216	115/240 (48%)
		ABC_membrane	697..963	CDD:279056
		ABC_MTABC3_MDL1_MDL2	1017..1252	CDD:213216

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100059
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810