DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG3156 and Abcb8

DIOPT Version :10

Sequence 1:NP_569844.2 Gene:CG3156 / 30994 FlyBaseID:FBgn0023536 Length:692 Species:Drosophila melanogaster
Sequence 2:NP_083296.2 Gene:Abcb8 / 74610 MGIID:1351667 Length:717 Species:Mus musculus


Alignment Length:717 Identity:258/717 - (35%)
Similarity:384/717 - (53%) Gaps:95/717 - (13%)


- Green bases have known domain annotations that are detailed below.


  Fly    14 TLRVRKSSQIRLSTSYNHHLGRCLHHRTARSLQHSLP--PPNRYHSHLHPTLRMPWWCMRRGFAQ 76
            |....:||..|||:    ||.|.:.....:...| ||  ||   .||..|:.    ||       
Mouse    27 TFSAARSSDDRLSS----HLLRTVAQLRVQLRAH-LPRAPP---ASHWSPSA----WC------- 72

  Fly    77 SSKWLARNAKANLPTAVGAGIVPAPVKMGRSQYGRLLSLTKSE-----------------KWVL- 123
               |:.           |..:|||.:    .|:.||..:...|                 .|.| 
Mouse    73 ---WVG-----------GTLVVPAVL----WQHPRLCLIALCEAKESPPAQPTRAPELRFNWKLF 119

  Fly   124 -------TAGIGCLVV----SSAITMSVPLFLGKVIDVV--FNKSGMDS--AAMAKLGEYSVLLF 173
                   ...:|..:|    ::.:.:.:||.||:::::|  :.:..|.|  :...||....:||:
Mouse   120 WHFLHPHLLALGAAIVLALGAALVNVQIPLLLGQLVEIVAKYTRDHMGSFVSESRKLSVQLLLLY 184

  Fly   174 GIFVLGGFANFARVHLFGNAALRIVRSLRSRLYRSMLMQEVGWFDTKGTGELINRLSNDTLMVGT 238
            |:   .|...|..:.|..:...|:...:|..|:.|:|.|::.:||.|.||:|::||:.|.....:
Mouse   185 GV---QGLLTFGYLVLLSHIGERMAMDMRKALFSSLLRQDIAFFDAKKTGQLVSRLTTDVQEFKS 246

  Fly   239 SLSQNVSDGLRS-VAMIG--VGTGMMIYTSPQLAAVSALVVPAMAGMAIVYGRYVRRITKVELDK 300
            |....:|.|||| ..:||  |...|:   ||:|..:.|:|.||:.|:..:.|..:|::::...::
Mouse   247 SFKLVISQGLRSCTQVIGSLVSLSML---SPRLTLMLAVVTPALMGVGTLMGSGLRKLSRQCQEQ 308

  Fly   301 YAEIMKFAEERFGNVKTVKTFCREQQEVAAFDGKLD----EALQIGYKETRARAIFFGLTGFCGN 361
            .|.....|:|..|||:||:.|..|::|...:..:|:    :|.::|    |..|:|.||:....|
Mouse   309 IARATGVADEALGNVRTVRAFAMEKREEERYQAELESCCCKAEELG----RGIALFQGLSNIAFN 369

  Fly   362 FIIISVLYYGGTLVLQDSLTIGALTAFMLYAGYVAISMNGLSNFYSQLNKGIGASERIWEILDRE 426
            .:::..|:.||:||....|..|.|.:|::.:..|..||..||..:.|:.:|:.|..|::|.:...
Mouse   370 CMVLGTLFIGGSLVAGQQLKGGDLMSFLVASQTVQRSMASLSVLFGQVVRGLSAGARVFEYMALS 434

  Fly   427 CSIPIDKG-VVPLEKPVGEVGFQNVFFTFPTRPESAVLTDFSLNLMPGTTTAVVGRSGSGKTTIA 490
            ..||:..| .:|.:...|.:.||||.|::|.||...||.||:|.|..|...|:||:||.||||:|
Mouse   435 PVIPLTGGYCIPNKDIRGSITFQNVTFSYPCRPGFNVLKDFTLKLPSGKIVALVGQSGGGKTTVA 499

  Fly   491 LLMLRLYDPQGGTVHLDGIDLRTVNPQWLRNN-IGAVSQEPVLFSCSIRENILYGANPGETPSPE 554
            .|:.|.|||:.|:|.|||.||||:||.|||.. ||.:|||||||:.:|.|||.:|....   |.|
Mouse   500 SLLERFYDPEAGSVTLDGHDLRTLNPSWLRGQVIGFISQEPVLFATTIMENIRFGKLDA---SDE 561

  Fly   555 RLQQVIEDANVSQFTDQLPDGLDTLVGQRGMMLSGGQKQRVAIARALIKNPAILILDEATSALDA 619
            .:.....:||..:|....|||..|:||:||..||||||||:||||||||.|.:||||||||||||
Mouse   562 EVYTAAREANAHEFISSFPDGYSTVVGERGTTLSGGQKQRLAIARALIKQPTVLILDEATSALDA 626

  Fly   620 VSENLVQNALDNLIQGRTVLTIAHRLSTIRNADQIAVLSDGKIVEQGSYNELMGIQEGVFRELVA 684
            .||.:||.|||....|||||.|||||||:|.|..|.|:::|::.|.|::.||:. :.|::.||:.
Mouse   627 ESERVVQEALDRASAGRTVLVIAHRLSTVRAAHSIIVMANGQVCEAGTHEELLK-KGGLYSELIR 690

  Fly   685 SQ 686
            .|
Mouse   691 RQ 692

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG3156NP_569844.2 MdlB 103..687 CDD:440747 234/626 (37%)
Abcb8NP_083296.2 MdlB 116..696 CDD:440747 230/591 (39%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 695..717
Blue background indicates that the domain is not in the aligned region.

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