Protein Alignment CG3156 and abcb8

DIOPT Version :10

• Sequence 1: NP_569844.2
• Gene: CG3156 / 30994
• FlyBaseID: FBgn0023536
• Length: 692
• Species: Drosophila melanogaster
• Sequence 2: NP_001017544.1
• Gene: abcb8 / 548340
• ZFINID: ZDB-GENE-050410-6
• Length: 714
• Species: Danio rerio
• Alignment Length: 737
• Identity: 256/737 - (34%)
• Similarity: 394/737 - (53%)
• Gaps: 90/737 - (12%)

  Fly     5 CTRLTHLCTTLRVRKSSQIRLSTSYNHHLGRCLHHRTARSL-QHSLPPPNRYHSHLHP------- 61
            |:|||....|       ..||.:|          |:|...| ||.    ||..:|..|
Zfish     7 CSRLTRGTVT-------SDRLLSS----------HKTRDFLFQHL----NRRGNHSAPWSSSQIP 50

  Fly    62 ----TLRMPWWCMRRGFAQSSKWL----------------------ARNAKANL--PTA-----V 93
                |:.:|   :.|.:.|:.|.|                      |....|.|  |:|     |
Zfish    51 STQLTVGVP---VLRIWRQAQKLLRLTSRQQPRPPSIALKFILGPAALTVTARLLGPSAHCEADV 112

  Fly    94 GAGIVPAPV----KMGRSQYGRLLSLTKSEKWVLTAGIGCLVVSSAITMSVPLFLGKVIDVVFNK 154
            ....||..|    |:....:..|....:.:.:.|...|.....::|:.:.:||.||.:::||...
Zfish   113 NNNKVPLEVQVKEKIPEFSWAVLWEFVRPQLFALMGAILLAFGAAALNIQIPLMLGDLVNVVARH 177

  Fly   155 SGMDSAAMAKLGEY-------SVLLFGIFVLGGFANFARVHLFGNAALRIVRSLRSRLYRSMLMQ 212
                  ...:.|.|       :|.|.|::.|.|......:.|......|:...:|:.|:.|:|.|
Zfish   178 ------MREQAGHYMRDIQAPAVKLLGLYALQGLLTSGYIILLSRVGERVAADMRTTLFTSLLRQ 236

  Fly   213 EVGWFDTKGTGELINRLSNDTLMVGTSLSQNVSDGLRSVAMIGVGTGMMIY-TSPQLAAVSALVV 276
            ::.:||...||:|:|||::|.....:|....:|.||||.... ||..:.:| .||:|..::.:|:
Zfish   237 DIAFFDANKTGQLVNRLTSDIQEFKSSFKLVISQGLRSATQT-VGCFVSLYFISPKLTGLTVVVL 300

  Fly   277 PAMAGMAIVYGRYVRRITKVELDKYAEIMKFAEERFGNVKTVKTFCREQQEVAAFDGKLDEALQI 341
            |.:.|...:.|.::|::::...::.|:....|:|..|||:||:.|..|.:|:..:..::.::..:
Zfish   301 PCLVGAGALIGSFLRKLSRKAQEQVAKATGVADEALGNVRTVRAFAMEDRELEMYAAEVQKSAAM 365

  Fly   342 GYKETRARAIFFGLTGFCGNFIIISVLYYGGTLVLQDSLTIGALTAFMLYAGYVAISMNGLSNFY 406
            ........|:|.||:....|.|::..::.||:|:.:|.|:.|.|.:|::.:..|..|:..:|..:
Zfish   366 NETLGTGIAVFQGLSNIVLNCIVLGTIFAGGSLMARDDLSPGDLMSFLVASQTVQRSLASISILF 430

  Fly   407 SQLNKGIGASERIWEILDRECSIPI-DKGVVPLEKPVGEVGFQNVFFTFPTRPESAVLTDFSLNL 470
            .|:.:|:.|..|::|.|..:.|:|: ..|.:||:..:|.|.|.|:.|::||||.:.:|..|||.|
Zfish   431 GQMVRGMSAGARVFEYLALDPSVPLTGGGRIPLDSLMGRVDFMNISFSYPTRPGNQILKHFSLTL 495

  Fly   471 MPGTTTAVVGRSGSGKTTIALLMLRLYDPQGGTVHLDGIDLRTVNPQWLRNN-IGAVSQEPVLFS 534
            .|..|.|:||.||.||:|:|.|:.|.|||..|.|.|||:|:||::|.|||.: ||.:|||||||.
Zfish   496 PPCKTVAIVGESGGGKSTVAALLERFYDPSSGVVMLDGLDIRTLDPSWLRGHVIGFISQEPVLFG 560

  Fly   535 CSIRENILYGANPGETPSPERLQQVIEDANVSQFTDQLPDGLDTLVGQRGMMLSGGQKQRVAIAR 599
            .|:.|||.:| .|..|.:  .:....:.||...|.....||.:|:||:||:.||||||||:||||
Zfish   561 TSVMENIRFG-KPSATDA--EVVSAAKQANAHNFITGFADGYNTVVGERGVTLSGGQKQRIAIAR 622

  Fly   600 ALIKNPAILILDEATSALDAVSENLVQNALDNLIQGRTVLTIAHRLSTIRNADQIAVLSDGKIVE 664
            ||:|||:|||||||||||||.||.:||.|||....|||||.||||||||:.||.|.|:|:|:|||
Zfish   623 ALVKNPSILILDEATSALDAESERVVQEALDRATTGRTVLIIAHRLSTIQAADLICVMSNGRIVE 687

  Fly   665 QGSYNELMGIQEGVFRELVASQ 686
            .|::.||:. :.|::.||:..|
Zfish   688 AGTHLELLS-KGGLYAELIKRQ 708

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3156	NP_569844.2	MdlB	103..687	CDD:440747	224/594 (38%)
abcb8	NP_001017544.1	MdlB	131..708	CDD:440747	222/587 (38%)