Protein Alignment CG3156 and Abcb11

DIOPT Version :9

• Sequence 1: NP_569844.2
• Gene: CG3156 / 30994
• FlyBaseID: FBgn0023536
• Length: 692
• Species: Drosophila melanogaster
• Sequence 2: NP_001350421.1
• Gene: Abcb11 / 27413
• MGIID: 1351619
• Length: 1321
• Species: Mus musculus
• Alignment Length: 621
• Identity: 212/621 - (34%)
• Similarity: 320/621 - (51%)
• Gaps: 66/621 - (10%)

  Fly   116 TKSEKWVLTAGIGC-----------LVVSSAIT------------MSVPLFLGKV--------ID 149
            :..:.|::..|..|           ::|...:|            :|:|   .||        |:
Mouse    55 SSKDNWLMFMGSVCALLHGMAQPGMIIVFGILTDIFVEYDIERQELSIP---EKVCMNNTIVWIN 116

  Fly   150 VVFNKS----------GMDSAAMAKLGEYSVLLFGIFVLGGFANFARVHLFGNAALRIVRSLRSR 204
            ..||::          .::|..:...|.|:.:...:.:||.|    ::.|:.....|.:|.:|..
Mouse   117 SSFNQNMTNGTSCGLVDINSEVIKFSGIYAGVGVAVLILGYF----QIRLWVITGARQIRKMRKF 177

  Fly   205 LYRSMLMQEVGWFDTKGTGELINRLSNDTLMVGTSLSQNVSDGLR--SVAMIGVGTGMMIYTSPQ 267
            .:|.::..|:||||....|||.:|.|:|...:..:::..::..|:  |.|:.|:..|  .|...:
Mouse   178 YFRRIMRMEIGWFDCTSVGELNSRFSDDINKIDEAIADQMALFLQRLSTALSGLLLG--FYRGWK 240

  Fly   268 LAAVSALVVPAMAGMAIVYGRYVRRITKVELDKYAEIMKFAEERFGNVKTVKTFCREQQEVAAFD 332
            |..|...|.|.:...|.|.|..|.:.|::||..||:....|:|...:::||..|..|.:||..::
Mouse   241 LTLVILAVSPLIGIGAAVIGLSVAKFTELELKAYAKAGSIADEVLSSIRTVAAFGGENKEVERYE 305

  Fly   333 GKLDEALQIGYKETRARAIFFG----LTGFCGNFIIISVLYYGGTLVLQD-SLTIGALTAFMLYA 392
            ..|..|.:.|..:......|.|    |..||    .....:||..|||.: ..|.|.|....|..
Mouse   306 KNLMFAQRWGIWKGMVMGFFTGYMWCLIFFC----YALAFWYGSRLVLDEGEYTPGTLIQIFLCV 366

  Fly   393 GYVAISMNGLSNFYSQLNKGIGASERIWEILDRECSIPIDKG-VVPLEKPVGEVGFQNVFFTFPT 456
            ...|:::...|:.....:.|..|:..|::.:||:..:....| ...|::..||:.|.||.|.:|:
Mouse   367 IIAAMNIGNASSCLEIFSTGCSAASSIFQTIDRQPVMDCMSGDGYKLDRIKGEIEFHNVTFHYPS 431

  Fly   457 RPESAVLTDFSLNLMPGTTTAVVGRSGSGKTTIALLMLRLYDPQGGTVHLDGIDLRTVNPQWLRN 521
            |||..:|.:.|:.:.||.|||.||.||:||:|...|:.|.|||..|.|.|||.|:|::|.:|||:
Mouse   432 RPEVKILNNLSMVIKPGETTAFVGSSGAGKSTALQLIQRFYDPCEGMVTLDGHDIRSLNIRWLRD 496

  Fly   522 NIGAVSQEPVLFSCSIRENILYGANPGETPSPERLQQVIEDANVSQFTDQLPDGLDTLVGQRGMM 586
            .||.|.|||||||.:|.|||..|.   |..:.|.:.|..:|||...|...||...|||||:.|..
Mouse   497 QIGIVEQEPVLFSTTIAENIRLGR---EEATMEDIVQAAKDANAYNFIMALPQQFDTLVGEGGGQ 558

  Fly   587 LSGGQKQRVAIARALIKNPAILILDEATSALDAVSENLVQNALDNLIQGRTVLTIAHRLSTIRNA 651
            :|||||||||||||||:.|.||:||.||||||..||..||.||:.:..|.|::::||||||:|:|
Mouse   559 MSGGQKQRVAIARALIRKPKILLLDMATSALDNESEAKVQGALNKIQHGHTIISVAHRLSTVRSA 623

  Fly   652 DQIAVLSDGKIVEQGSYNELMGIQEGVFRELVASQA 687
            |.|.....|..||:|::.||:. ::||:..||..|:
Mouse   624 DVIIGFEHGTAVERGTHEELLE-RKGVYFMLVTLQS 658

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3156	NP_569844.2	MdlB	106..687	CDD:224055	211/619 (34%)
		ABC_membrane	127..395	CDD:279056	76/315 (24%)
		ABC_MTABC3_MDL1_MDL2	447..686	CDD:213216	122/238 (51%)
Abcb11	NP_001350421.1	AAA	29..1314	CDD:333001	212/621 (34%)
		Interaction with HAX1. /evidence=ECO:0000250	651..674		3/8 (38%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	662..722

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100059
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900