Protein Alignment CG3156 and mdl1

DIOPT Version :9

• Sequence 1: NP_569844.2
• Gene: CG3156 / 30994
• FlyBaseID: FBgn0023536
• Length: 692
• Species: Drosophila melanogaster
• Sequence 2: NP_595751.1
• Gene: mdl1 / 2541285
• PomBaseID: SPBC9B6.09c
• Length: 726
• Species: Schizosaccharomyces pombe
• Alignment Length: 678
• Identity: 257/678 - (37%)
• Similarity: 384/678 - (56%)
• Gaps: 31/678 - (4%)

  Fly     9 THLCTTLRVRKSSQIRLSTSYNHHLGRCLHHRTARS----LQHSLPPPNRYHSHLHP--TLRMPW 67
            |.|..|......|..:||:..|..|.......::.|    .::|.|.|  :...:.|  :|....
pombe    45 TLLLPTPNAEYYSTSKLSSQVNVSLNSLSQKASSGSKIYPFKNSFPLP--FSRSILPIRSLAFLK 107

  Fly    68 WCMRRGFAQSSKWLARNAKANLPTAVGA-GIVPAPVKMGRSQYGRLLSLTKSEKWVLTAGIGCLV 131
            .|:|......||    :.:|...:.:.. |.:..|.|  :....||.:|.:.:.|........|:
pombe   108 LCVRHNSTVPSK----DEQAQDISKINTNGTLQTPNK--KVNVFRLFTLARGQGWNFFIAGSLLL 166

  Fly   132 VSSAITMSVPLFLGKVIDVVFNKSGMDSAAMAKL----GEYSVLLFGIFVLGGFANFARVHLFGN 192
            |||.:|||:|..:||::|.  ..|| ||:....:    |.:.:.|.|:|.||...||.|:.....
pombe   167 VSSGVTMSIPYIVGKILDA--GSSG-DSSVTHIMGIPSGTFYIGLLGLFFLGSACNFGRIITLRL 228

  Fly   193 AALRIVRSLRSRLYRSMLMQEVGWFDTKGTGELINRLSNDTLMVGTSLSQNVSDGLRSVAMIGVG 257
            .:.|||..||:||:...:..:..:||....|:||:||:.|:.:||.|||..:||||||......|
pombe   229 LSERIVSRLRARLFAKCMSLDGAFFDFHKHGDLISRLTTDSSIVGKSLSMYLSDGLRSSVSAIAG 293

  Fly   258 TGMMIYTSPQLAAVSALVVPAMAGMAIVYGRYVRRITKVELDKYAEIMKFAEERFGNVKTVKTFC 322
            .|||:|.|.:|....:|:||.:|..|..||.|||::::...|...::.:.:||:..||:|.:.|.
pombe   294 IGMMLYVSMRLTGYMSLIVPPIALGAFFYGEYVRKLSRTTQDALGDLTRVSEEKLANVRTTQAFL 358

  Fly   323 REQQEVAAFDGKLDEALQIGYKETRARAIFFGLTGFCGNFIIISVLYYGGTLVLQDSLTIGALTA 387
            .|:|||..::..:.....:..:|..|..||||.|||.||..:|::|..||.:|....:|:|.|::
pombe   359 GERQEVNRYNDYIRNLFVLAKREAFASGIFFGSTGFLGNATVIAILALGGRMVAAGDITVGQLSS 423

  Fly   388 FMLYAGYVAISMNGLSNFYSQLNKGIGASERIWEILDRECSIPIDKGVVPLEKPVGE--VGFQNV 450
            |:||..|...|:.|||..::.:.||:||:.|::|:||.:..|....| :|:...||:  :.|:||
pombe   424 FLLYTVYAGGSIVGLSGCFTDIMKGLGAASRLFELLDAKPKIAPTVG-IPVPVTVGKAILSFRNV 487

  Fly   451 FFTFPTRPESAVLTDFSLNLMPGTTTAVVGRSGSGKTTIALLMLRLYDPQGGTVHLDGIDLRTVN 515
            .|.:||||.:::..:.|.::.|||..|:|..||.||:||:.|:||.|.|..|.:..||:|:.|.|
pombe   488 GFAYPTRPSASIFDNLSFDIHPGTNVAIVAPSGGGKSTISQLLLRFYAPSSGKILADGVDISTYN 552

  Fly   516 PQWLRNNIGAVSQEPVLFSCSIRENILYGANPGETPSPERLQQVIEDANVSQFTDQLPDGLDTLV 580
            ....|::.|.|.|||||||.:|.|||.||.:   ..|.|.::...:.||.| |....|:...|.|
pombe   553 VHQWRSHFGLVGQEPVLFSGTIGENIAYGKS---NASQEEIEDAAKRANCS-FVLSFPEKWSTQV 613

  Fly   581 GQRGMMLSGGQKQRVAIARALIKNPAILILDEATSALDAVSENLVQNALDNLIQGR--TVLTIAH 643
            |.||:.||||||||:||||||::|||.|||||||||||..:|.:|...:.:|:..|  |.:||||
pombe   614 GTRGLQLSGGQKQRIAIARALLRNPAFLILDEATSALDGEAEVMVDKTIQSLMHNRSMTTITIAH 678

  Fly   644 RLSTIRNADQIAVLSDGKIVEQGSYNEL 671
            :|:|||.||||.|:.|||::||||:..|
pombe   679 KLATIRRADQIIVVGDGKVLEQGSFERL 706

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3156	NP_569844.2	MdlB	106..687	CDD:224055	235/574 (41%)
		ABC_membrane	127..395	CDD:279056	100/271 (37%)
		ABC_MTABC3_MDL1_MDL2	447..686	CDD:213216	113/227 (50%)
mdl1	NP_595751.1	MdlB	141..723	CDD:224055	235/574 (41%)
		ABC_membrane	164..430	CDD:279056	100/268 (37%)
		P-loop_NTPase	484..720	CDD:304359	113/227 (50%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	181	1.000	Domainoid score	I807
eggNOG	1	0.900	-	-		E2759_KOG0058
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H6474
Inparanoid	1	1.050	416	1.000	Inparanoid score	I352
OMA	1	1.010	-	-		QHG54509
OrthoFinder	1	1.000	-	-		FOG0000243
OrthoInspector	1	1.000	-	-		oto101770
orthoMCL	1	0.900	-	-		OOG6_100059
Panther	1	1.100	-	-	O	PTHR24221
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1969
SonicParanoid	1	1.000	-	-		X2387
TreeFam	1	0.960	-	-
	14	13.860