Protein Alignment CG3156 and Abcb4

DIOPT Version :9

• Sequence 1: NP_569844.2
• Gene: CG3156 / 30994
• FlyBaseID: FBgn0023536
• Length: 692
• Species: Drosophila melanogaster
• Sequence 2: NP_036822.1
• Gene: Abcb4 / 24891
• RGDID: 620248
• Length: 1278
• Species: Rattus norvegicus
• Alignment Length: 613
• Identity: 223/613 - (36%)
• Similarity: 335/613 - (54%)
• Gaps: 55/613 - (8%)

  Fly    92 AVGAGIVPAPVKMGRSQYGRLLSLTKSEKWVLTAGIGCLVVSSAITMSVPLFLGKVIDVVFNKSG 156
            |.|:|:   |:.|  ..:|.:     ::|:|..||...|.|:.:::|..|   |::::
  Rat    63 AHGSGL---PLMM--IVFGEM-----TDKFVDNAGNFSLPVNFSLSMLNP---GRILE------- 107

  Fly   157 MDSAAMAKLGEYSVLLFGIFVLGG---FANFARVHLFGNAALRIVRSLRSRLYRSMLMQEVGWFD 218
                  .::..|:....|   |||   .|.:.:|..:..||.|.:|.:|.:.:.::|.||:||||
  Rat   108 ------EEMTRYAYYYSG---LGGGVLLAAYIQVSFWTLAAGRQIRKIRQKFFHAILRQEMGWFD 163

  Fly   219 TKGTGELINRLSNDTLMVGTSLSQNVSDGLRSVAMIGVGTGMMIYTSPQLAAVSALVVPAMAGMA 283
            .|||.||..||::|...:...:...|....:::|....|..:......:|..| .:.:.|:.|::
  Rat   164 IKGTTELNTRLTDDISKISEGIGDKVGMFFQAIATFFAGFIVGFIRGWKLTLV-IMAITAILGLS 227

  Fly   284 -IVYGRYVRRITKVELDKYAEIMKFAEERFGNVKTVKTFCREQQEVAAFDGKLDEALQIGYKETR 347
             .|:.:.:...:..||..||:....|||..|.::||..|..:.:|:..:...|:.|.:||.|:..
  Rat   228 TAVWAKILSTFSDKELAAYAKAGAVAEEALGAIRTVIAFGGQNKELERYQKHLENAKKIGIKKAI 292

  Fly   348 ARAIFFGLTGFCGNFIIISVLY-----YGGTLVLQDSLTIG-ALTAFM-LYAGYVAISMNGLSNF 405
            :..|..|:.     |::|...|     ||.|||:....||| |:|.|. :..|  |.|:...:..
  Rat   293 SANISMGIA-----FLLIYASYALAFWYGSTLVISKEYTIGNAMTVFFSILIG--AFSVGQAAPC 350

  Fly   406 YSQLNKGIGASERIWEILDRECSIP--IDKGVVPLEKPVGEVGFQNVFFTFPTRPESAVLTDFSL 468
            ........||:..|::|:|....|.  .::|..| :...|.:.|.:|.|::|:|....:|...:|
  Rat   351 IDAFPNARGAAYVIFDIIDNNPKIDSFSERGHKP-DSIKGNLEFSDVHFSYPSRANIKILKGLNL 414

  Fly   469 NLMPGTTTAVVGRSGSGKTTIALLMLRLYDPQGGTVHLDGIDLRTVNPQWLRNNIGAVSQEPVLF 533
            .:..|.|.|:||.||.||:|...|:.|||||..||:.:||.|:|..|.:.||..||.||||||||
  Rat   415 KVKSGQTVALVGNSGCGKSTTVQLLQRLYDPTEGTISIDGQDIRNFNVRCLREFIGVVSQEPVLF 479

  Fly   534 SCSIRENILYGANPGETPSPERLQQVIEDANVSQFTDQLPDGLDTLVGQRGMMLSGGQKQRVAIA 598
            |.:|.|||.||..   ..:.:.:::.:::||...|..:||...|||||.||..||||||||:|||
  Rat   480 STTIAENIRYGRG---NVTMDEIKKAVKEANAYDFIMKLPQKFDTLVGDRGAQLSGGQKQRIAIA 541

  Fly   599 RALIKNPAILILDEATSALDAVSENLVQNALDNLIQGRTVLTIAHRLSTIRNADQIAVLSDGKIV 663
            |||::||.||:|||||||||..||..||.|||...:|||.:.|||||||:||||.||...||.||
  Rat   542 RALVRNPKILLLDEATSALDTESEAEVQAALDKAREGRTTIVIAHRLSTVRNADVIAGFEDGVIV 606

  Fly   664 EQGSYNELMGIQEGVFRELVASQAFGSR 691
            ||||::||:. :||::..||..|..||:
  Rat   607 EQGSHSELIK-KEGIYFRLVNMQTSGSQ 633

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3156	NP_569844.2	MdlB	106..687	CDD:224055	215/593 (36%)
		ABC_membrane	127..395	CDD:279056	74/278 (27%)
		ABC_MTABC3_MDL1_MDL2	447..686	CDD:213216	125/238 (53%)
Abcb4	NP_036822.1	PTZ00265	29..1271	CDD:240339	223/613 (36%)
		ABC_membrane	58..342	CDD:279056	84/315 (27%)
		ABC_MTABC3_MDL1_MDL2	392..628	CDD:213216	125/239 (52%)
		Interaction with HAX1. /evidence=ECO:0000269|PubMed:15159385	622..646		5/12 (42%)
		ABC_membrane	714..984	CDD:279056
		ABC_MTABC3_MDL1_MDL2	1033..1272	CDD:213216

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100059
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810